培菲康与乳果糖预防肝性脑病的疗效比较  

Comparison of the efficacy of Bifico and lactulose in the prevention of hepatic encephalopathy

作　　者：朱陈[1] 孙源源[1] 金燕[1] 

机构地区：[1]江苏省南通市第三人民医院消化内科,南通226000

出　　处：《上海医药》2014年第23期17-18,21,共3页Shanghai Medical & Pharmaceutical Journal

摘　　要：目的 :比较培菲康和乳果糖预防肝硬化上消化道出血后肝性脑病的疗效。方法 :将2013年1月-2014年1月收入本院100例确诊肝硬化合并上消化道出血的患者随机分为培菲康组和乳果糖组(各50例),在常规治疗的基础上,分别加用培菲康及乳果糖,2周后观察疗效。结果 :治疗后比较,两组肝性脑病发生率无显著性差异(P>0.05)。培菲康组血氨含量及数字连接实验(NCT)均优于乳果糖组(P<0.05)。结论 :培菲康的治疗效果优于乳果糖,且不良反应少。Objective： To compare the efifcacy of Biifco and lactulose in the prevention of hepatic encephalopathy after upper gastrointestinal hemorrhage hepatic of cirrhosis.Methods： One hundred cases of patients with hepatic cirrhosis complicated with upper gastrointestinal hemorrhage were randomly divided into a Biifco group and a lactulose group with 50 cases each from January, 2013 to January, 2014. Biifco was given in the Biifco group while lactulose in the lactulose group on the basis of routine therapy, and the curative effect was observed after 2 weeks.Results： There was no signiifcant difference in the incidence of hepatic encephalopathy between two groups after treatment （P〉0.05）. Ammonia content and the number connection test experiment （NCT） are much better in the Biifco group than in the lactulose group （P〈0.05）.Conclusion： The efifcacy of Biifco with less adverse reaction is better than lactulose.

关 键 词：培菲康 乳果糖 肝性脑病 

分 类 号：R747.9[医药卫生—神经病学与精神病学]