温控医用腔内灌注泵数学模型及实验研究  

Experimental Research of the Mathematical Model in a Thermostatic Medical Infusion Pump

作　　者：李小霞[1] 严荣国[1] 葛斌[1] 杨池[1] 陈倩[1] 

机构地区：[1]上海理工大学医疗器械与食品学院,上海200093

出　　处：《中国医学物理学杂志》2015年第1期104-109,共6页Chinese Journal of Medical Physics

基　　金：国家自然科学基金(30200390);上海市科学技术委员会项目(10441901400)

摘　　要：目的:温控医用灌注泵是一种能够提供温的冲洗液的医疗器械,主要用于腹部手术创伤处的冲洗。介绍一款温控医用腔内灌注泵,并采用PID(Proportional Integral Derivative)控制器将灌注泵出水温度控制在某一合理范围内。方法:为了达到以上目的,我们对设计好的温控医用灌注泵的传递函数数学模型及其实验进行研究。首先介绍了温控医用灌注泵的工作原理,其次通过实验确定系统的阶跃响应,并在Matlab中绘制温控医用灌注泵的阶跃响应曲线,确定灌注泵在不同流速情况下的传递函数数学模型。然后运用Ziegler-Nichols公式计算出特定数学模型所对应的PID控制参数。最后运用Matlab软件中的Simulink工具箱对该数学模型和PID控制器的控制参数进行仿真,并将控制参数运用到实际系统中。结果:仿真结果显示,输出曲线能够在较短的时间内达到设定的输出值;实验结果显示,在不同流速时,系统的输出液温度能够3 min内达到需求的范围,最终使得灌注泵输出液体的温度恒定在36.0°C±1.5°C以内。结论:仿真及实验证明,该系统设计合理,得到的数学模型能够准确描述系统的特性,数学模型准确可靠,实验方法合理可行。Objective The thermostatic medical infusion pump is a kind of medical device that can be used to provide warm solu-tion for wound cleaning and flushing during abdominal surgery. To introduce a new kind of thermostatic infusion pump and usethe proportional integral derivative （PID） controller to keep the temperature at the outlet of the pump at a certain temperature.Methods In order to achieve above goals, some research on the designed thermostatic medical infusion pump was done. Firstly,the working principle of the system was introduced. Then the step response of the system was determined by experiments, andthe step response curve was plotted to determine the mathematical transfer function models under different flow rate by usingMatlab software. And then the controlling parameters were derived by the Ziegler-Nichols formula. Finally, the mathematicalmodels and the parameters of the PID controller were simulated using the Simulink toolbox of MATLAB and the parameterswere also applied to the real controlling system. Results Results of simulation show that the temperature can reach the set valuein a shorter time; also results of experiments show that the temperature at the outlet can reach a certain temperature within 3 min-utes, and finally keep it at 36.0℃ ＋ 1.5 ℃. Conclusion Results of simulation and experiments both show that the design is rea-sonable and the mathematical model was accurate and reliable.

关 键 词：灌注泵 温控器 阶跃响应 PID控制器 传递函数 

分 类 号：TP13[自动化与计算机技术—控制理论与控制工程]