^(125)I粒子条剂量分布研究  

Dosimetry of consecutive linear arranged ^(125)I seeds

作　　者：杨敏捷[1] 罗剑钧[1] 刘清欣[1] 刘凌晓[1] 张雯[1] 方主亭[1] 杨清慧[1] 颜志平[1] 

机构地区：[1]复旦大学附属中山医院介入治疗科,200032

出　　处：《介入放射学杂志》2015年第1期59-63,共5页Journal of Interventional Radiology

基　　金：上海市卫生和计划生育委员会2013年度先进适宜技术推广(2013SY060)

摘　　要：目的探讨连续线状排列125I粒子条剂量分布。方法通过玻璃剂量计及IP板测量粒子条剂量立体分布并与计算软件结果比较。结果玻璃剂量计测量数据与软件计算相关性良好(r>0.99,P=0.000)。除R=0.5 cm处外,两者差异性无统计学意义(P<0.05)。IP板测定2 cm以内粒子间存在自吸收现象,自吸收的量约22.8%。结论连续线状排列的125I粒子条辐射等计量分布类似于柱形体,为其应用于腔内放射治疗提供理论依据。Objective To investigate the radiation distribution of consecutive linear arranged125 I seeds in vitro. Methods The in vitro 3- D radiation distribution was measured by radiophoto- luminescent glass detectors and imaging plate（IP） using a SM- 2 model. The results were then compared with the data obtained from the software calculation. Results Strong correlation existed between the software calculation and data obtained from radiophoto- luminescent glass detector measurements（r 0.99, P = 0.000）. No statistically significant difference was found between the two methods except at R = 0.5 cm area（P 0.05）.A proportion about 22.8% self- absorption within 2 cm was observed when IP measurement was used.Conclusion The isodose lines of consecutive linear arranged125 I seeds conform to tubular structure, which provides theoretical basis for its application in intraluminal brachytherapy.

关 键 词：剂量学 125I粒子 近距离放射治疗 

分 类 号：R730.55[医药卫生—肿瘤]