室管膜母细胞瘤的CT和MRI表现  

CT and MRI Manifestations of Ependymoblastomas

作　　者：熊伟[1] 许乙凯[1] 严承功[1] 谭相良[1] 吕晓飞[2] 

机构地区：[1]广东省广州市南方医科大学南方医院影像中心,510515 [2]广东省广州市中山大学肿瘤防治中心影像与微创介入中心

出　　处：《临床放射学杂志》2015年第1期140-143,共4页Journal of Clinical Radiology

摘　　要：目的探讨室管膜母细胞瘤的CT和MRI表现特点及其鉴别诊断。方法回顾性分析5例经手术病理证实的室管膜母细胞瘤患者的临床及影像学资料,5例均接受MRI平扫及增强扫描,其中2例同时接受CT平扫。结果 5例室管膜母细胞瘤中4例为单发病灶,其中1例发生于右侧额叶,3例发生于脑室内(右侧侧脑室、左侧侧脑室及四脑室各1例)。1例为多发病灶,主体位于双侧额叶侵犯胼胝体膝部并脑室及鞍上池多发播散转移。肿瘤体积2.6 cm×2.4 cm×3.4 cm^5.7 cm×5.6 cm×5.4 cm。CT平扫1例发生于左侧侧脑室内病灶表现为大片状钙化,边界清晰,瘤周无水肿,另1例发生于双侧额叶病灶表现为不均匀稍高密度,边界不清,可见大片水肿。MRI平扫T1WI多表现为等稍低信号,T2WI呈不均匀高信号,增强扫描呈均匀或不均匀强化,3例见肿瘤内囊变。结论CT和MR检查能准确显示室管膜母细胞瘤部位、范围及周围受累情况,但是影像学表现无特异性,定性诊断有赖于病理检查。Objective To investigate CT and MRI manifestations of ependymoblastomas. Methods The imaging and clinical data of 5 patients with pathologically-proved ependymoblastoma were retrospectively analyzed. Both plain and con- trast-enhanced MRI scans were performed in all 5 patients, and additional plain CT scanning was employed in 2 patients. Results Of the 5 cases, the lesion of ependymoblastoma was single in 4, which were located at right frontal lobe （ n = 1 ） and in cerebral ventricle （n = 3 ）, including the right lateral ventricle （ n = 1 ）, the left lateral ventricle （ n = 1 ） and the fourth ventricle （ n = 1 ）. The remaining one case had multiple lesions, the main part of the lesions were situated at bilateral frontal lobe involving the genu of the corpus callosum accompanied with multiple disseminated metastases in the ventricle and suprasellar cistern. The volume of the tumors ranged from 2.6 × 2.4 × 3.4 cm3 to 5.7 × 5.6 × 5.4 cm3. In one case with the lesion being located in left lateral ventricle, plain CT scans revealed large area of calcification with clear boundary and no peritumoral edema. In another case whose lesion was located in the bilateral frontal lobes, plain CT scans showed inhomogeneous slightly high density shadow with unclear border and massive edema. MRI showed that the lesion presented as iso-intensity or hypo-intensity signal on T1WI and inhomogeneous hyper-intensity signal on T2WI. On contrast-enhanced MR! scans, the lesions showed homogeneous or inhomogeneous enhancement. Cystic degeneration of the tumor was ob- served in 3 cases. Conclusion CT and MRI can correctly display the site and extent of ependymoblastoma as well as the involvement of neighboring structures, but its imaging findings are nonspecific, therefore, the qualitative diagnosis should depend on pathological examination.

关 键 词：室管膜母细胞瘤 体层摄影术 X线计算机 磁共振成像 

分 类 号：R739.4[医药卫生—肿瘤] R445.2[医药卫生—临床医学]