斑蝥酸钠维生素B_6注射液联合射波刀治疗中晚期肝癌临床观察  

Clinical observation of middle-late stage primary hepatic carcinoma patients treated by Disodium Cantharidinate and vitamin B6 injection combined Cyberknife therapy

作　　者：刘建民[1] 

机构地区：[1]广西中医药大学附属瑞康医院放疗科,广西南宁530011

出　　处：《现代肿瘤医学》2015年第3期392-394,共3页Journal of Modern Oncology

摘　　要：目的:评估斑蝥酸钠维生素B6注射液联合射波刀治疗中晚期肝癌近期疗效及不良反应的发生情况。方法:2007年12月-2011年7月有75例患者确诊为原发性肝癌,分期为T3-4期,随机分为斑蝥酸钠维生素B6注射液联合射波刀治疗(联合组,40例)和单纯射波刀治疗(对照组,35例),比较两组的近期疗效及不良反应。结果:联合组近期总有效率(CR+PR)为87.5%,对照组近期总有效率(CR+PR)为77.1%,联合组在近期疗效和生活质量以及急性不良反应方面均优于对照组(P<0.05)。结论:斑蝥酸钠维生素B6注射液联合射波刀治疗中晚期肝癌,疗效确切,毒副作用小,是一种安全有效的治疗方法。Objective：To evaluate the recent efficiency and the radiation toxicity of primary hepatic carcinoma treated with Disodium Cantharidinate and vitamin B6 injection combined Cyberknife therapy. Methods ： Between De- cember 2007 and July 2011,75 patients with primary hepatic carcinoma, stage W3 -4, were divided randomly into Diso- dium Cantharidinate and vitamin B6 injection combined Cyberknife therapy （combined group, 40 cases） and simple Cyberknife therapy（ control group,35 cases）. Results ：The response rate（ CR ＋ PR） in combined group was 87.5% , and 77.1% in control group. The recent efficiency, quality of life and acute radiation toxicity were better in combined group than control group. Conclusion：Disodium Cantharidinate and vitamin B6 injection combined Cyberknife therapy is a safe and effective therapeutic method to treat middle -late stage primary hepatic carcinoma.

关 键 词：原发性肝癌 斑蝥酸钠维生素B6注射液 射波刀 

分 类 号：R735.7[医药卫生—肿瘤]