六种牙齿充填修复材料的释氟与再充氟性能研究  

Fluoride release and recharge properties of six restorative materials

作　　者：桂亚婕[1] 赵信义[1] 李石保[1] 唐立辉[1] 龚旭[1] 

机构地区：[1]第四军医大学口腔医学院口腔材料教研室 军事口腔医学国家重点实验室,西安710032

出　　处：《中华口腔医学杂志》2015年第1期28-32,共5页Chinese Journal of Stomatology

基　　金：国家自然科学基金（81171002）

摘　　要：目的 评价6种牙齿充填修复材料的释氟和再充氟性能,以期为临床选择和应用提供参考.方法 选择材料A（FujiⅦ玻璃离子水门汀）、材料B（FujiⅡLC光固化玻璃离子水门汀）、材料C（Beautifil离子体复合树脂）、材料D（Compoglass F复合体）、材料E（Charisma普通复合树脂）及材料F（实验Ⅰ型释氟性复合树脂）作为实验材料,制备直径10 mm、厚1 mm的圆片,每组10个试样.每个试样浸于5 ml去离子水中,用氟离子选择电极测定浸出液氟离子量,浸泡1～7d每天测定,8～28d3d测定1次,计算每日释氟量.于浸泡28 d后用氟化泡沫对试样充氟4min,继续测定试样每日释氟量,连续测定7d;再充氟并测定氟释放7d,重复3次.结果 浸泡1d后所有材料均表现最大的释氟量,材料A释氟量最大[（99.68±15.21） μg·cm^-2·d^-1,其次为材料B[（37.12±1.67） μg·cm^-2·d^-1,再次为材料F和D[分别为（22.93±1.53）和（15.28±0.70） μg·cm^-2·d^-1,材料C和E释氟量较小[分别为（2.40±0.52）和（0.11±0.02） μg·cm-2· d-1],各组间差异有统计学意义（P＜0.05）.浸泡2d后释氟量显著下降,随后（7～ 28 d）释氟量下降缓慢;浸泡1～28 d内,材料A和B的释氟量始终大于其他材料（P＜0.01）,其次是材料D和F,显著大于材料C和E（P＜0.01）.所有材料充氟1d后的释氟量均较充氟前显著增加,形成释氟高峰,充氟2d后的释氟量又显著下降.充氟1d后材料A的释氟量超过40 μg· cm^-2·d^-1大于其他材料（P＜0.01）;其次是材料B,释氟量超过25 μg· cm^-2·d^-1大于除A外的其他材料（P＜0.01）;材料C、D、F释氟量相近,在15～ 20μg·cm^-2·d^-1间;材料E释氟量较小,＜1.5 μg· cm^-2·d^-1结论 玻璃离子水门汀类材料的释放及再充氟能力最强,其次是复合体和释氟性复合树脂,离子体复合树脂释氟能力小,但其再充氟能力与复合体和释氟性复合树脂相当,普通复合树脂的释氟及再充氟能力�Objective To evaluate the F-releasing and recharging properties of six dental restorative materials.Methods Disc specimens 10 mm in diameter and 1 mm in thickness were prepared from 6 different dental restorative materials：Fuji Ⅶ [glass ionomer cement（GIC）],Fuji lⅡ LC（light-curing,GIC）,Beautifil（giomer）,Compoglass F（compomer）,Charisma（composite） and Experimental Ⅰ （a fluoride releasing composite）,with 10 discs for each material.Specimens were dipped in 5 ml deionized water and Frelease was detected using a fluoride-specific ion electrode every day from 1-7 days and every three days from 8-28 days.On day 28,specimens were exposed to a fluoride foam for 4 min and then dipped in water,then the F-concentration was detected every day for a week.The specimens were exposed to fluoride foam and fluoride release was detected repeatedly for three times.Results All materials presented the highest F release on the first day after dipping and the F-release sharply decreased after 24 h and slowly decreased after 3 days.On the first day,Fuji Ⅶ presented the highest F-release[（99.68± 15.21） μg· cm-2· d-1],followed by Fuji Ⅱ LC[（37.12±1.67） μg·cm^-2·d^-1,Experimental Ⅰ [（22.93±1.53） μg·cm^-2·d^-1,Compoglass F[（15.28±0.70） μg· cm-2· d-1],Beautifil[（2.40±0.52） μg· cm-2· d-1] and Charisma[（0.11±0.02） μg· cm-2· d-1].Within 28 days of dipping,both Fuji Ⅶ and Fuji Ⅱ LC released more F-than other materials did（P〈0.05）,followed by Compoglass F and Experimental Ⅰ,and Beautifil and Charisma released the least F-（P〈0.01）.After Fuptake,all materials released the highest F-on the first day and presented sharply decrease after 24 h and slowly decrease after 2 days.On the first day after F-uptake,Fuji Ⅶ presented the highest F-release （〉40 μg· cm-2· d-1）,much more than other materials（P〈0.01）,followed by Fuji Ⅱ LC（〉25 μ.g· cm-2· d-1）.Beautifil,Compoglass F and Experimental Ⅰ were close in F-release value（15-20

关 键 词：氟化物 复合树脂类 玻璃离聚物粘固剂 

分 类 号：R783.1[医药卫生—口腔医学]