心脑宁胶囊在脑梗死偏瘫患者治疗和康复中作用的研究  

The study on the therapeutic effect and rehabilitation of Xinnaoning capsule in hemiplegia patient with acute cerebral infarction

作　　者：陈兵[1] 陈娟[1] 

机构地区：[1]解放军第309医院神经内科,北京100091

出　　处：《北京医学》2015年第2期200-201,共2页Beijing Medical Journal

摘　　要：目的探讨心脑宁胶囊在脑梗死偏瘫患者治疗和康复中的临床疗效。方法选取2012年1月至2014年1月我院神经内科收治的60例脑梗死偏瘫患者,采用随机对照方法将其分为观察组和对照组。对照组(B组)给予常规治疗、康复训练和二级预防;观察组(A组)在此基础上口服心脑宁胶囊(贵州安泰药业有限公司,国药准字H20025697,规格:0.45 g/粒),每次1.35 g,每日3次口服,连续用药6个月。于患者入院时及系统康复训练6个月后进行神经功能残缺(NIHSS)评分,并采用Brunnstrom分级法评定肢体运动功能、Barthel氏指数(BI)评定日常生活能力(ADL)。结果经过6个月的康复治疗,60例患者NIHSS评分和BI均有不同程度改善。A组康复前后NIHSS评分差值为5.2±1.8,B组为3.5±1.3;A组康复前后BI差值为40.0±11.0,B组为21.2±7.3;A组改善程度均显著高于B组(P<0.05)。结论对于脑梗死偏瘫患者,心脑宁胶囊可有效辅助改善患者临床症状,促进神经功能恢复。Objective To investigate the therapeutic effect of Xinnaoning capsule for hemiplegia patients with a-cute cerebral infarction. Methods A total of 60 patients with hemiplegia complicated with acute cerebral infarction from January 2012 to January 2014 were included. Patients were divided into the observation group （group A） and the control group （group B） randomly. Patients in group B were given conventional therapy and rehabilitation training, while patients in group A were given Xinnaoning capsule combined with conventional therapy and rehabilitation training. The evaluation was done before and after treatment. NIHSS was observed and Motor function was assessed with Brunnstrom Grade, ADL was assessed by Barthel Index （BI）. Results After 6 month of treatment, the change of NIHSS before and after in group A （5.2±1.8） were more significant than that of group B （3.5±1.3）. So did the BI [group A （40.0±11.0）, group B （21.2±7.3）]. Conclusion Xinnaoning capsule can effectively improve the patients＆#39; clinical symptoms, promote neural function recov-ery.

关 键 词：心脑宁胶囊 脑梗死 康复 

分 类 号：R743.3[医药卫生—神经病学与精神病学]