膀胱副节瘤临床诊治与病理特点分析  

Clinical diagnosis and treatment of bladder paragangliomas and its pathological characteristics analysis

作　　者：豆颖[1] 闫哲[2] 

机构地区：[1]河南省商丘市第一人民医院病理科,476000 [2]河南省商丘市第一人民医院心内科,476000

出　　处：《中国现代药物应用》2015年第5期8-10,共3页Chinese Journal of Modern Drug Application

摘　　要：目的探讨膀胱副节瘤临床诊治与病理特点。方法 5例膀胱副节瘤患者作为本次的研究对象,并对患者的临床资料进行回顾性分析,观察膀胱副节瘤临床诊治与病理特点。结果 5例患者均顺利完成手术,其中术中出血量为61~253 ml。切除肿瘤完整,呈椭圆形或圆形,直径1.6~2.6 cm,表面无明显包膜,切面呈灰白色或者黄褐色。3例术前血压升高,术后血压在3 d内降至正常范围。本组5例患者均获得随访,随访时间60个月,其中1例患者术后48个月发生腰椎转移,其余患者均未发生复发现象。结论膀胱副节瘤较为罕见,诊断时应重视临床表现,例如与排尿有关的头晕、头痛等高血压发作症状及肉眼血尿等,同时影像学及实验室检查均有利于对本病进行诊断及鉴别,术前不主张活检,手术为首选治疗手段,术后重视随访。Objective To investigate the clinical diagnosis and treatment of bladder paragangliomas and its pathological characteristics. Methods There were 5 patients with bladder paragangliomas as the research subjects of this study. Their clinical data were retrospectively analyzed for observation of clinical diagnosis and treatment and pathological characteristics of bladder paragangliomas. Results All of the 5 patients received successful surgery, and the intraoperative bleeding volume was 61-253 ml. Tumor resection was complete as oval or round in 1.6~2.6 cm of diameter without obvious coated surface, and the incision surface was hoary or tawny. There were 3 cases with elevated blood pressure, which returned to normal range within 3 d. Follow-up was taken on all the 5 cases for 60 months. Among them, there was 1 case with lumbar vertebra metastasis in 48 months af- ter treatment, and the other cases had no relapse. Conclusion Bladder paragangiiomas is rare, and its clinical manifestations are important in diagnosis, such as hypertensive symptom of dizziness related with micturition and headache and visible hematuresis. Imageology and laboratory examination are all helpful for diagnosis and iden- tification of the disease. Preoperative biopsy is not advocated. The main treatment method is surgery, and postop- erative follow-up is essential.

关 键 词：膀胱副节瘤 手术 病理诊断 鉴别诊断 

分 类 号：R737.14[医药卫生—肿瘤]