肥胖与卵巢癌的相关性  

Correlation between obesity and ovarian cancer

作　　者：李霞辉[1] 张学梅[1] 蒋葵[2] 

机构地区：[1]大连医科大学附属第二医院肿瘤内科,116027 [2]大连大学医学院

出　　处：《国际肿瘤学杂志》2015年第2期150-152,共3页Journal of International Oncology

基　　金：国家科技支撑计划（2012BAK25800）

摘　　要：肥胖不仅增加卵巢癌的发生危险，而且与卵巢癌的不良预后相关。其病因学机制可能与肥胖引起雌激素、胰岛素及胰岛素样生长因子水平升高，以及多种脂肪细胞因子等因素共同作用相关，影响卵巢癌的治疗效果和预后。因此，保持合适的体重可以预防和控制卵巢癌的发生和发展。Obesity increases the risk of ovarian cancer, and it is associated with the poor prognosis of ovarian cancer. Its pathogenic mechanism may be associated with the increased level of serum estrogen, insulin and insulin-like growth factors-1 induced by obesity and a variety of adipocytokines, which has an impact on the therapeutic result and prognosis of ovarian cancer. Maintaining a proper weight may prevent the development of ovarian cancer.

关 键 词：肥胖症 卵巢肿瘤 人体质量指数 

分 类 号：R737.31[医药卫生—肿瘤]