Clinical Efficacy of Toric Orthokeratology in Myopic Adolescent with Moderate to High Astigmatism  

作　　者：Ming Luo Shengsheng Ma Na Liang 

机构地区：[1]Department of Ophthalmology, Guangzhou Red Cross Hospital [2]the Fourth Affiliated Hospital of Jinan University Medical College

出　　处：《Eye Science》2014年第4期209-213,218,共6页眼科学报（英文版）

摘　　要：Purpose:.To observe the efficacy of toric design orthokeratology.(ortho-k).for correcting myopia and astigmatism in myopic adolescents with moderate to high astigmatism.Methods:.This was a self-controlled clinical study..Twentyfour subjects(42 eyes).aged 9 to 16 years with myopia of 2.50-6.00 D complicated with rule astigmatism of 1.50-3.50 D were fitted with Lucid Night Toric Ortho-k Lenses(LUCID,KOREA)..The changes in uncorrected visual acuity(UCVA),spherical degree, refraction, axial length(AL),.and corneal status were assessed at baseline, 1 night, 1 week, 1 month, 3months, 6 months, and 1 year after the commencement of ortho-k lens wear.Results: The success rate of the first lens fit was 92.8%. The UCVA after ortho-k wearing was improved significantly compared to the baseline during each visit(all P<0.01), and became stable 1 month after ortho-k. The manifest myopia was significantly reduced from(-3.41±1.27) D to(-0.41±0.37) D by toric ortho-k and the degree of astigmatism from(-1.81±0.53)D to(-0.41±0.39) D after 1 month of lens wear(P<0.01).The mean AL was(24.47 ±0.91) mm at baseline, which did not significantly differ from(24.49 ±0.87) mm and(24.48 ±0.94) mm after 6 months and l year,.respectively,.of lens wear(both P >0.05)..Grade 1 corneal staining was observed at 1week(23.8%),.1 month(21.4%), and 1 year(16.7%) following lens wear, and was improved by lens cleaning,.discontinuing lens wear, and moistening the cornea with eye drops.No severe adverse events were reported.Conclusion: The toric ortho-k lens was effective and safe for correction of low to moderate myopia in children with moderate to high astigmatism..The lens also effectively controlled axial length elongation during 1 year of observation..However,the long-term efficacy remains to be elucidated.Purpose： To observe the efficacy of toric design orthokeratology （ortho-k） for correcting myopia and astigmatism in myopic adolescents with moderate to high astigmatism. Methods： This was a self-controlled clinical study. Twentyfour subjects（42 eyes） aged 9 to 16 years with myopia of 2.50- 6.00 D complicated with rule astigmatism of 1.50-3.50 D were fitted with Lucid Night Toric Ortho-k Lenses （LUCID,KO- REA）. The changes in uncorrected visual acuity （UCVA）, spherical degree, refraction, axial length （AL）, and corneal status were assessed at baseline, 1 night, 1 week, 1 month, 3 months, 6 months, and 1 year after the commencement of ortho-k lens wear. Results： The success rate of the first lens fit was 92.8%. The UCVA after ortho-k wearing was improved significantly compared to the baseline during each visit （all P〈0.01）, and became stable 1 month after ortho-k. The manifest myopia was significantly reduced from （-3.41±1.27） D to （-0.41±0.37） D by toric ortho-k and the degree of astigmatism from （-1.81±0.53）D to （-0.41±0.39） D after 1 month of lens wear （P〈0.01）. The mean AL was （24.47±0.91） mm at baseline, which did not significantly differ from （24.49±0.87） mm and （24.48±0.94） mm after 6 months and 1 year, respectively, of lens wear （both P〉0.05）. Grade 1 corneal staining was observed at 1 week （23.8%）, 1 month （21.4%）, and 1 year （16.7%） following lens wear, and was improved by lens cleaning, discontinuing lens wear, and moistening the cornea with eye drops. No severe adverse events were reported. Conclusion： The toric ortho-k lens was effective and safe for correction of low to moderate myopia in children with moderate to high astigmatism. The lens also effectively controlled axial length elongation during 1 year of observation. However, the long-term efficacy remains to be elucidated.

关 键 词：临床疗效 青少年 角膜 散光 近视 镜头清洁 磨损 矫正 

分 类 号：R778.1[医药卫生—眼科]