超声“萤火虫”成像显示乳腺钙化灶的价值和意义：与钼靶X线对照  

Value of MicroPure imaging of ultrasonography in display of breast calcification： comparison with mammography

作　　者：贾妹妮 康春松[1] 陈晓燕[1] 薛继平[1] 杨青梅[1] 房建秀[1] 

机构地区：[1]山西医学科学院山西医科大学附属大医院超声科,太原030032

出　　处：《中华超声影像学杂志》2015年第1期50-54,共5页Chinese Journal of Ultrasonography

摘　　要：目的评价超声“萤火虫”成像对乳腺钙化灶的显示率，探讨其临床应用价值。方法141例乳腺疾病患者行钼靶X线、常规超声及超声“萤火虫”成像检查，以钼靶X线为参照标准，评价超声“萤火虫”成像对钙化灶的显示率及不同形态钙化灶的显示情况；以病理结果为金标准构建ROC曲线，比较常规超声、常规超声联合超声“萤火虫”成像、常规超声联合钼靶X线诊断乳腺良恶性病灶的价值。结果超声“萤火虫”成像显示肿块伴钙化的特异性较常规超声低（88．14％对100％，P〈0．05），灵敏性、准确性较常规超声高（100％对62．79％，93．14％对84．31％，P〈0．05）；显示单纯钙化的特异性、准确性较常规超声低（9．26％对100％，43．87％对65．96％，P〈0．05），灵敏性较常规超声高（100％对20．00％，P〈0．05）。钼靶X线中钙化形态为点状57例，无定形性8例，粗糙不均匀8例，多形性10例，超声“萤火虫”成像中均为点状强回声。常规超声、常规超声联合超声“萤火虫”成像、常规超声联合钼靶X线诊断乳腺良恶性病灶的ROC曲线下面积分别为0．881、0．858、O．932。结论超声“萤火虫”成像可提高乳腺肿块内钙化显示的灵敏性、准确性，对肿块内钙化的诊断有一定价值；显示钙化特异性较低，不能区分钙化的形态，与常规超声相结合，不能提高乳腺良恶性诊断的准确度。Objective To evaluate the value of MicroPure imaging system of ultrasonography in display of breast calcification, and explore its clinical application value. Methods One hundred and forty-one patients underwent by mammography, conventional ultrasound imaging and MicroPure imaging, the mammography results were reference standard, observing the display rate of MicroPure imaging for calcification,and the value of MicroPure imaging in the display of calcification with different shapes on mammography. As the pathologic diagnosis was golden standard, the accuracy of diagnosis of conventional ultrasound,conventional ultrasound combined with MicroPure imaging, conventional ultrasound combined with mammography were evaluated with receiver operating characteristic（ROC） curve. Results The display case of calcifications within breast masses., the specificity of MicroPure imaging was lower than conventional ultrasound（88.14% vs 100%, P ~ 0.05）, the sensitivity and accuracy were higher than conventional ultrasound（100% vs 62.79% ,93.14% vs 84.31%, P %0.05）. The display case of microcalcifications within normal breast tissue： the specificity and accuracy of MicroPure software system were lower than conventional ultrasound（9.26 % vs 100 %, 43.87% vs 65.96 %, P %0.05）, the sensitivity was higher than conventional ultrasound （100~ vs 20.00%, P %0.05）. The punctate calcification,amorphous calcification, rough uneven, pleomorphic calcifications on mammography were all hyperechoic spots on MicroPure software system. The area under the ROC curve of the conventional ultrasound, conventional ultrasound combined with MicroPure imaging,conventional ultrasound combined with MicroPure imaging was 0.881, 0.858,0.932, respectively. Conclusions MicroPure imaging has some clinical value on microcalcifications within breast masses,which can improve its sensitivity and accuracy. The specificity of MicroPure imaging diagnostic ultrasound imaging of microcalcifications were lower,and it can not distinguish between different s

关 键 词：超声检查 乳房 乳房X线摄影术 乳腺疾病 钙质沉着症 

分 类 号：R737.904[医药卫生—肿瘤]