纤维蛋白胶运用于翼状胬肉手术的临床观察  

Clinical observation on fibrin glue application during pterygium surgery

作　　者：雷琦峰[1] 蔡维[1] 

机构地区：[1]湖北医药学院附属东风医院眼科,中国湖北省十堰市442000

出　　处：《国际眼科杂志》2015年第2期364-366,共3页International Eye Science

摘　　要：目的:观察纤维蛋白胶运用于翼状胬肉切除联合自体结膜移植术的临床效果。方法:选取60例60眼原发性鼻侧翼状胬肉患者随机分为试验组(纤维蛋白胶组)和对照组(缝线组)各30例30眼。行翼状胬肉切除联合自体结膜移植术,试验组采用纤维蛋白胶粘合固定植片,对照组采用10-0尼龙线缝合固定植片。术后随访6mo,观察手术时间、术后疼痛、异物感、并发症以及复发。结果:试验组手术时间(24.5±6.5min)较对照组(35.2±5.4min)短,两组差异有统计学意义(P<0.05)。术后患者疼痛和异物感试验组较对照组减轻(P<0.05)。两组均未发生术后严重并发症,试验组结膜下出血发生率低于控制组(P<0.05),6mo时纤维蛋白胶组1例(3%)复发,缝线组3例(10%)复发。结论:纤维蛋白胶运用于翼状胬肉手术固定结膜植片能减轻患者术后不适,减少手术时间及术后并发症,是一种安全有效的方法。AlM： To observe the clinical results of pterygium excision combined with conjunctival autograft transplantation using fibrin glue.METHODS：A total of 60 patients （60 eyes） with primary nasal pterygium were randomly divided into two groups：the fibrin glue group （ experimental group, 30 eyes） and suture group （ control group, 30 eyes ） . All patients underwent pterygium excision combined with conjunctival autograft transplantation. ln the experimental group autograft was attached to sclera with fibrin glue while in control group 10-0 polyamide was used. The patients were followed up for 6mo. The time of operation, post operation comfort, complications and recurrence were evaluated.RESULTS：The average surgical time was 24. 5 ± 6. 5min with fibrin glue group while 35. 2 ± 5. 4min with suture group, with statistically significant difference between two groups （P〈0. 05）. Pain and foreign body sensation was significantly less with fibrin glue group than that in the control group （ P 〈0. 05 ）. No severe postoperative complication occurred both in two groups. The incidence of subconjunctival hemorrhage in the experimental group was lower than that in the control group （P〈0. 05）. 1 case （3%） of fibrin glue group, 3 cases （10%） of suture group had recurrence at the end of follow up 6mo.CONCLUSlON：lt＇s a safe and effective way to attach conjunctival autograft during pterygium surgery by fibrin glue. lt can reduce surgical time, postoperative complications and relieve postoperative discomfort.

关 键 词：翼状胬肉 纤维蛋白胶 自体结膜移植 复发 

分 类 号：R779.6[医药卫生—眼科]