阿司匹林联合三七制剂对脑梗死复发的干预效果研究  

An effective study on intervening recurrence of cerebral infarction with Aspirin plus notoginseng pharmaceutics

作　　者：高建岭[1] 崔娟[1] 

机构地区：[1]南阳医学高等专科学校,河南南阳473000

出　　处：《中医临床研究》2015年第1期72-73,共2页Clinical Journal Of Chinese Medicine

摘　　要：目的:探讨阿司匹林联合三七制剂对脑梗死复发的干预效果。方法:选取75例脑梗死病人,随机分为两组,对照组单用小剂量肠溶阿司匹林抗凝,治疗组在此基础上加用三七制剂抗凝,观察治疗前后凝血指标、血流变和再梗死率变化,以及出血事件发生率。结果:治疗组纤维蛋白原、PT、APPT、血液黏度及再梗死率与治疗前有显著性差异(P<0.05),且与对照组治疗后比较亦有显著性差异(P<0.05),两组出血事件发生率经比较无显著性差异(P>0.05)。结论:阿司匹林联合三七制剂可延长脑梗死患者凝血时间,改善血液黏度,降低再梗死率。长期服用对脑梗死病人具有协同预防复发作用。Objective： To investigate intervention effects of Aspirin plus notoginseng pharmaceutics on recurrence of cerebral infarction. Methods： 75 patients were randomly divided into two groups, the control group was given low-dose Aspirin anticoagulant, another was given notoginseng pharmaceutics anticoagulant more. Coagulation, blood flow changes, reinfarction rate and the incidence of bleeding were observed. Results： Compared with before treatment and control group Fibrinogen, PT, APPT, blood viscosity and reinfarction rate in the treatment group was better （P〈0.05）, while the incidence of bleeding was not statistically significant （P〉0.05）. Conclusion： Aspirin plus notoginseng pharmaceutics can prolonged clotting time of cerebral infarction patients, blood viscosity was improved, and reinfarction was reduced, and it can prevent cerebral infarction.

关 键 词：脑梗死 阿司匹林 三七制剂 复发 干预 

分 类 号：R743.33[医药卫生—神经病学与精神病学]