代谢综合征与结直肠肿瘤关系的研究进展  

Review on the relationship between metabolic syndrome and colorectal neoplasms

作　　者：杨静[1] 吴杰[1] 

机构地区：[1]武汉市中心医院消化内科,430000

出　　处：《中华临床医师杂志（电子版）》2014年第22期129-132,共4页Chinese Journal of Clinicians(Electronic Edition)

摘　　要：大量临床研究表明,代谢综合征可能是结直肠肿瘤发病的重要危险因素。两类疾病的关联机制可能涉及结肠黏膜慢性炎症、结肠黏膜屏障破坏和肠道菌群结构改变等。尽管具体机制尚不明确,但代谢综合征因素对结直肠肿瘤的防治工作及基础研究具有重要意义。Growing evidence has supported that metabolic syndrome （MS） could be an important risk factor of colorectal tumorigenesis. Multifactorial mechanisms could take part in the relationship between MS and colorectal neoplasms, such as inflammation of colonic mucosa, injury of mucosal barrier function and alteration of the microbiome. In spite of unclear mechanisms of action, MS components and related diseases have significant roles in prevention and fundamental research of colorectal neoplasms.

关 键 词：代谢综合征X 结直肠肿瘤 炎症 肠道菌群 

分 类 号：R735.3[医药卫生—肿瘤]