适宜发展中国家与地区的宫颈癌快速筛查技术的研究及意义  

Screening technologies to advance rapid testing for cervical cancer prevention in developing countries

作　　者：乔友林[1] 

机构地区：[1]中国医学科学院北京协和医学院肿瘤医院,北京100021

出　　处：《中华预防医学杂志》2015年第2期110-111,共2页Chinese Journal of Preventive Medicine

摘　　要：中国医学科学院肿瘤医院为首的团队开发了适宜发展中国家与地区的宫颈癌快速筛查技术，即人乳头瘤病毒（HPV）DNA检测技术——careHPV检测技术。该检测技术是国际上首次研发成功的一种简单、快速、准确、安全并且成本较低的技术，并且首次以临床疾病结局为终点指标，验证了careHPV检测技术在人群中筛查宫颈癌的准确性，与目前采用的标准HPV检测方法和细胞学检测结果接近，高于醋酸染色肉眼观察法（VIA）。careHPV检测技术的推广和应用将有助于促进我国并带动其他发展中国家的宫颈癌防治工作，加快缩短发展中国家与发达国家在宫颈癌防治方面的差距，对于全球降低宫颈癌发病率、死亡率具有重要意义。The rapid screening testing for cervical cancer prevention in low- and middle-income countries, careHPV assay, is developed by Cancer Hospital, Chinese Academy of Medical Sciences. The careHPV assay is the first HPV DNA detection technique worldwide, which is simple, fast, accurate, safe, and inexpensive. The testing technique was verified using clinical outcome as the endpoint, and its accuracy was similar to the current standard HPV detection technique and even higher than VIA. The popularization and application of careHPV could tremendously contribute to cervical cancer prevention in China as well as other developing countries. This would also reduce the disparity between developed and developing countries in cervical cancer prevention and help reduce the incidence and mortality of this disease.

关 键 词：宫颈肿瘤 快速筛查 HPV CareHPV 

分 类 号：R737.33[医药卫生—肿瘤]