慢性牙周炎与2型糖尿病的相互关系及影响因素分析  

The Relationship Between Chronic Periodontitis and type 2 Diabetes and Influence Factors Analysis

作　　者：徐洁[1] 

机构地区：[1]福建省立医院口腔科,福建福州350001

出　　处：《航空航天医学杂志》2015年第2期146-148,共3页Journal of Aerospace medicine

摘　　要：目的探讨慢性牙周炎与2型糖尿病的相互关系及影响因素。方法选取2012年~2014年收治的单纯慢性牙周炎患者30例（对照组1）,慢性牙周炎与2型糖尿病患者（观察组）60例,健康群体30例（对照组2）。分别对其糖化血红蛋白（Hb Alc）、C反应蛋白（hs-CRP）、血糖水平等进行检测。将观察组平均分为两组,第1组行单纯降血糖治疗,第2组行牙周病基础＋一般降血糖治疗。结果观察组Hb Alc、hs-CRP及空腹血糖水平显著高于对照组。治疗后,观察组2的Hb Alc、hs-CRP、龈沟出血指数及牙周袋深度显著改善。观察组1 Hb Alc显著改善,其他指标无明显变化。观察组2改善程度显著高于观察组1。经Logistic回归性分析,Hb Alc、hsCRP、龈沟出血指数均具有统计学意义。结论慢性牙周炎与2型糖尿病存在双向影响关系,可促使病情加重恶化。故对Hb Alc、hs-CRP、龈沟出血指数等危险因素有效干预对其治疗具有重大意义。Objective To explore the relationship between chronic periodontitis and type 2 diabetes and its influen- cing factors. Methods From 2012 - 2012 chose simple chronic periodontitis patients 30 cases （ control group 1 ） and chronic periodontitis patients with type 2 diabetes （ observation group） 60 cases, 30 cases of healthy group （ control group 2）. Respectively the glyeated hemoglobin （HbAlc） and e -reactive protein （hs CRP） and blood sugar levels such as detection. The observation group average divided into 2 groups, group 1 line of pure, fall blood sugar treatment group 2 lines of periodontal diseased foundation ＋ generally fall blood sugar treatment. Results The observation group＇s HbAlc, hs - CRP and fasting blood sugar level was significantly higher than the control group, which were statistically significant differences （all P 〈0.05 ）. After treatment, the observation group＇s 2 HbAlc, hs -CRP, gingival bleeding index and periodontal pocket depth was improved significantly, which were statistically significant differences （ all P 〈 0. 05 ）. Ob- servation group＇s 1 HbAlc improved significantly, and other indicators had no obvious changed. Observation group 2 im- proved degree of observation group was significantly higher than 1. By Logistic regression analysis, HbAle, hs - CRP, Gingival bleeding indexwere statistically significant. Conclusions Chronic periodontitis with a mutual relationship be- tween type 2 diabetes, can making an illness aggravating. In this paper, HbAlc, hs, CRP, Gingival bleeding indexand other risk factors for effective intervention for the treatment is of great significance.

关 键 词：牙周炎 糖尿病 相互关系 

分 类 号：R781.4[医药卫生—口腔医学] R587.1[医药卫生—临床医学]