钼靶X线摄片联合肿瘤相关标志物检测对乳腺癌的诊断价值  

Diagnostic Value of X-ray Combined with Detection of Tumor-related Markers in Serum of Breast Cancer

作　　者：刘海岭[1] 王妍[2] 张明焕[1] 李蕊[1] 徐占彪 

机构地区：[1]武警北京总队第三医院,北京100141 [2]空军航空医学研究所附属医院,北京100089

出　　处：《现代生物医学进展》2015年第5期912-914,共3页Progress in Modern Biomedicine

摘　　要：目的:探讨乳腺钼靶X射线摄片与血清糖类抗原15-3(CA15-3)、癌胚抗原(CEA)和骨桥蛋白(OPN)联合检测对乳腺癌的临床诊断价值。方法:选择在我院经手术和病理证实为乳腺癌的患者60例作为研究组,另选取60例健康体检者作为对照组。分别检测两组的血清CA15-3、CEA和OPN水平,并采用乳腺钼靶X射线检查。比较X射与血清学检测单独检测及联合检测的阳性率。结果:研究组患者血清CA15-3、CEA及OPN水平均显著高于对照组,差异具有统计学意义(P<0.05);血清CA15-3、CEA、OPN和钼靶X射线摄片联合检测的敏感性显著高于单独检测,差异具有统计学意义(P<0.05)。结论:对乳腺癌患者进行钼靶X射线摄片及肿瘤相关标志物检测可提高阳性检出率,有利于乳腺癌的早期诊断及治疗。Objective： To investigate the diagnostic value of mammography X-ray radiography and serum detection of carbohy- drate antigen 15-3 （CA15-3）, carcinoembryonic antigen （CEA） and osteopontin （OPN） for breast cancer. Methods： 60 cases with breast cancer who were treated in our hospital were selected as the study group, and 60 healthy volunteers were selected as a control group. The two groups were detected in serum CA15-3, CEA and OPN levels and the use of mammography X-ray examination. Comparison of X-ray-positive rate and serology testing and joint detection alone. Results： The study group serum CA 15-3, were significantly higher than CEA and OPN water, the difference was statistically significant（P〈0.05）; serum CA15-3, CEA, OPN and mammography X-ray radiogra- phy combined detection significantly higher detection sensitivity alone, the difference was statistically significant （P〈0.05）. Conclusion： Radiography and tumor-associated markers for breast cancer patients concluded the X-ray mammography can increase the positive detec- - tion rate for early diagnosis and treatment of breast cancer.

关 键 词：乳腺癌 钼靶X射线 肿瘤相关标志物 血清学检查 

分 类 号：R737.9[医药卫生—肿瘤]