手术治疗121例老年垂体腺瘤临床分析  

Clinical analysis of operation treatmen of 121 elderly patients with pituitary adenoma

作　　者：毛仁玲[1] 张法永[1] 高幸[1] 王知秋[1] 江澄川[1] 

机构地区：[1]复旦大学附属华山医院神经外科

出　　处：《老年医学与保健》2015年第1期35-37,共3页Geriatrics & Health Care

摘　　要：目的探讨老年垂体腺瘤的临床特点和手术治疗意义。方法回顾性分析了121例60岁及以上垂体腺瘤的临床资料。结果手术主要采用经鼻蝶窦入路，肿瘤全切除及次全切除91例，大部切除25例，部分切除5例。住院期间视力好转80例，占88．9％。随访MRI72例，肿瘤无复发或静止状态67例，复发需再次手术5例。术后生活自理率80％。结论多数老年垂体腺瘤初期的临床表现隐匿，发现时往往肿瘤大、压迫视神经，尽早鞍区MRI检查可明确诊断。手术切除肿瘤对老年垂体瘤有效、安全，尤其是经鼻蝶入路。Objective To investigate the clinical features and surgical treatment effects of pituitary adenoma in elderly patients. Methods A retrospective chart review was undertaken for 121 patients over the ages of 60 with pituitary adenoma. Results The pituitary adenomas were underwent resection by the transsphenoidal endonasal approach in predominant. The tumor total excision and subtotal excision were in 91 cases, large partial excision in 25 cases, partial excision in 5 cases. Vision improved in 80 cases during hospitalization, and the visual improvement rate was 88.9%. 72 cases were followed- up with MRI, and found that no tumor recurrence or static state in 67 cases, relapse and operation again in 5 cases. The rate of living by themselves was 80 % postoperation. Conclusions The early clinical manifestation were occult in most of elderly patients with pituitary adenoma. The tumors usually were large and the chiasmatic syndrome were present when the diagnosis were confirmed. Sellar area MRI was contributed to confirm the diagnosis. Surgical treatment of elderly patients with pituitary adenoma was effective and safe procedure, especially the transsphenoidal endonasal approach.

关 键 词：老年 垂体腺瘤 手术 

分 类 号：R736.4[医药卫生—肿瘤]