色素放大内镜对胃肠上皮化生及早期癌变的诊断价值  

Diagnostic value of magnifying chromoendoscopy for gastrointestinal metaplasia and early cancerization

作　　者：刘汝冰[1] 张国洲[1] 高达臣 闫永丽[1] 邵松涛[1] 许克伟 孙玉荣[1] 郑丽端[3] 

机构地区：[1]阜南县人民医院消化内科,安徽阜南236300 [2]阜南县人民医院病理科,安徽阜南236300 [3]华中科技大学同济医学院附属协和医院消化科,湖北武汉430022

出　　处：《临床荟萃》2015年第2期203-205,共3页Clinical Focus

基　　金：国家自然科学基金(81071997/H1617);市级科研基金项目(2011N56)

摘　　要：目的探究色素放大内镜对胃肠上皮化生及早期癌变的诊断价值。方法选取慢性胃炎患者164例,分别由同一名资深技师先后对患者进行普通内镜及染色放大内镜检查,并与病理检查结果进行对比,比较两种检测方法对胃黏膜肠上皮化生及早期癌变诊断的优劣。结果色素放大内镜对胃黏膜肠上皮化生及早期癌变诊断与病理诊断结果有极高的一致性(Kappa值=0.849、0.883,P<0.05)。色素放大内镜对肠上皮化生及胃早期癌变的敏感度(87.324%、87.805%),特异度(96.774%、98.374%)及准确度(92.683%、95.732%)明显大于普通内镜。结论色素放大内镜对胃黏膜肠上皮化生及胃早期癌变的诊断相对普通内镜检出率高,与病理结果一致性高。Objective To explore the value of magnifying chromoendoscopy for the diagnosis of gastrointestinal metaplasia and early cancerization.Methods A total of 164 patients with chronic gastritis received normal endoscopy and magnifying chromoendoscopy.The results were compared with the pathological findings so as to evaluate the pros and cons of the two methods for the diagnosis of gastric intestinal metaplasia and early cancerization.Results For the gastric intestinal metaplasia and early cancer,magnifying chromoendoscopy could get highly consistent results with the pathological examination（Kappa=0.849 and 0.883,P〈0.05）.The diagnostic sensitivity and specificity of magnifying chromoendoscopy were 87.324% and 96.774% for intestinal metaplasia and 87.805% and 98.374% for early gastric cancer,and its diagnostic accuracy could reach 92.683% and 95.732% for intestinal metaplasia and early gastric cancer,respectively.All the parameters were significantly higher than those of the ordinary endoscope.Conclusion For gastric intestinal metaplasia and early gastric cancer,magnifying chromoendoscopy has a higher detection rate than the ordinary endoscopic examination,which can get highly consistent results with the pathological findings.

关 键 词：胃炎 胃镜检查 化生 诊断技术和方法 

分 类 号：R573.3[医药卫生—消化系统]