经口内镜肌切开术治疗贲门失弛缓症的临床研究进展  

Peroral endoscopic myotomy for achalasia

作　　者：张游[1] 令狐恩强[1] 

机构地区：[1]解放军总医院消化科,北京100853

出　　处：《解放军医学院学报》2015年第2期193-196,共4页Academic Journal of Chinese PLA Medical School

基　　金：国家自然科学基金项目(81370584)~~

摘　　要：贲门失弛缓症的治疗目的主要是降低食管下括约肌压力,缓解吞咽困难的症状。由于该病具有症状反复的特点,因此,迫切需要一种疗效最优的治疗方法。经口内镜肌切开术是近年发展起来治疗贲门失弛缓症的微创新技术,能够有效地降低贲门失弛缓症患者食管下括约肌压力,改善其吞咽困难的症状,但是,对于其远期疗效有待进一步证实。本文就目前经口内镜肌切开术治疗贲门失弛缓症的适应证、使用器械、操作技术要点、临床疗效及并发症进行归纳总结。Treatment of achalasia mainly aims at lowering of the pressure of lower esophageal sphincter （LES） and remission of dysphagia. Owing to its characteristic of symptom recurrence, it is urgent for us to develop an optimal treatment for achalasia. Peroral endoscopic myotomy （POEM）, which has been developed in recent years, is a new minimally invasive technique for achalasia, and it can effectively lower the pressure of LES and improve the symptom of dysphagia. However, its long term efficacy for achalasia still remains to be confirmed. This review mainly describes the indications, equipments, technical aspects, clinical effects and complications of POEM for the treatment of achalasia.

关 键 词：贲门失弛缓症 经口内镜肌切开术 疗效 

分 类 号：R571[医药卫生—消化系统]