毒品依赖者的行为抑制功能的实验研究  

The experimental study of behavioral inhibition function of drug addicts

作　　者：杨涛 李欣娜 毛金铭[3] 

机构地区：[1]兰州市第一人民医院,兰州730050 [2]兰州市七里河区疾控中心,兰州730070 [3]西北师范大学心理学院,兰州730070

出　　处：《中国药物滥用防治杂志》2015年第1期13-14,39,共3页Chinese Journal of Drug Abuse Prevention and Treatment

摘　　要：目的:研究美沙酮维持治疗者和强制戒毒人员的行为抑制功能,进一步探讨美沙酮作为一种替代性药物对于毒品依赖者的意义。方法:通过行为实验的方法,采用E-prime编制程序来了解海洛因依赖者的行为抑制功能,使用SPSS17.0对数据进行统计分析。结果:强制戒毒者的行为抑制功能的表现明显弱于正常组和美沙酮组;美沙酮维持治疗者的行为抑制功能与正常人比较,没有显著差异;三组被试的反应正确率之间没有差异。结论:美沙酮维持治疗改善了毒品依赖者的行为抑制功能,对改变毒品依赖者的高危行为,减少与吸毒有关的违法犯罪等方面有重要的意义。Objective： To study the behavioral inhibition of drug addicts treated with methadone maintenance and compulsory detoxification, in order to explore the effects of methadone maintenance on the cognitive function of drug addicts. Methods： The core component of the executive function-response inhibition was investigated using a visual Oddball task programed by E-prime and then uses SPSS17.0 for statistical analysis of the data. Results： The performance of behavioral inhibition was significantly weaker in addicts treated in the compulsory detoxification center compared with normal control. There is no significant difference in the behavioral inhibition performance between methadone maintenance patient and the normal control, meanwhile, the mandatory groups have a better performance than the methadone maintenance treatment. There is no difference among the three groups for response accuracy. Conclusion： Methadone maintenance therapy improves the behavioral inhibition function of drug dependent persons. This result shows important significance in the changing high-risk behaviors of drug dependent persons and reducing drug-related crimes.

关 键 词：毒品依赖者 行为抑制功能 实验研究 

分 类 号：R749.64[医药卫生—神经病学与精神病学]