长脉宽1064nm Nd∶YAG激光或595nm脉冲染料激光或两者联合治疗会阴部婴幼儿血管瘤疗效分析  

The therapeutic efficacy analysis of long-pulsed 1 064 nm Nd∶YAG laser or 595 nm pulsed dye laser or combination of the above two lasers for the treatment of perineal infantile hemangioma

作　　者：郑卫风[1] 何葆华[1] 付俊[2] 刘玲[2] 

机构地区：[1]杭州整形医院皮肤美容科,浙江杭州310014 [2]第四军医大学西京皮肤医院,陕西西安710032

出　　处：《临床皮肤科杂志》2015年第2期116-119,共4页Journal of Clinical Dermatology

摘　　要：目的:总结分析长脉宽1 064 nm掺钕钇铝石榴石(Nd∶YAG)激光、595 nm脉冲染料激光(PDL)或两者联合治疗会阴部婴幼儿血管瘤临床疗效、不良反应及其影响疗效的有关因素。方法:应用长脉宽1 064 nm Nd∶YAG激光、脉冲染料激光或两者联合治疗会阴部婴幼儿血管瘤35例,治疗间隔4~8周。统计治疗效果并分析影响疗效的因素。结果:35例患儿,其中男3例、女32例,年龄40 d^2岁,皮损面积0.1~15 cm2。治疗有效率为100%,治疗次数1~5次。常见的不良反应为红肿和水疱,一般3~5 d内修复,其中2例出现糜烂及渗出,5例痊愈后皮肤质地有变化,2例遗留色素沉着,未见感染、瘢痕等其他不良反应。结论:长脉宽1 064 nm Nd∶YAG激光及595 nm脉冲染料激光治疗会阴部婴幼儿血管瘤安全有效,不良反应轻微,值得推广应用。Objectives： To analyze the clinical efficacy, adverse reaction and the factors related to the efficacy for the treat- ment of perineal infantile hemangioma by long-pulsed 1 064 nm Nd：YAG laser or 595 nm pulsed dye laser or combination of the two lasers. Methods： Thirty-five cases of perineal infantile hemangioma were treated with long-pulsed 1 064 nm Nd：YAG laser or 595 um pulsed dye laser or the combination of the two lasers. The course of treatment was 4-8 weeks. Statistical analysis of the efficacy and the factors influencing therapeutic effects were carried out. Results： Thirty-five cases, including 3 male and 32 female, aged 40 days to 2 years, and the areas of lesions ranged from 0.1-15 cm^2. The total effective rate was 100% after 1-5 times of treatment. The common adverse reactions were erythema, edema and blister, which healed within 3-5 days, The skin texture of 5 cases was changed after being cured, 2 cases had hypcrpigmentation, and infection, scar formation and other adverse reactions were not observed. Conclusions： Long-pulsed 1 064 nm Nd：YAG laser or 595 nm pulsed dye laser are safe and effective for the treatment of perineal iniantile hemangioma with mild adverse reactions, which can be widely used.

关 键 词：血管瘤 会阴部 婴幼儿 1 064nm ND:YAG激光 脉冲染料激光 

分 类 号：R732.2[医药卫生—肿瘤]