SBK LASIK和epi—LASIK矫治近视临床研究  

Clinical research on treatment of myopia by three refractive operations

作　　者：杜改萍[1,2] 黄一飞[2] 李珍[1] 

机构地区：[1]解放军第401医院眼科,青岛266071 [2]解放军总医院眼科,北京100853

出　　处：《中国实用眼科杂志》2015年第1期38-41,共4页Chinese Journal of Practical Ophthalmology

基　　金：中国博士后基金资助（2012M521877） （杜改萍李珍）;100853北京.解放军总医院眼科（杜改萍黄一飞）通信作者：李珍,Email

摘　　要：目的比较SBK、LASIK和epi-LASIK手术矫治近视的临床效果。方法前瞻性临床试验研究。对2009年5月至2010年3月在解放军总医院近视中心行屈光手术的病人，根据机械角膜板层刀的不同分为LASIK组、SBK组和epi-LASIK（epipolis laser-insitu keratomilensis）组，分别于手术前、术后1、7d，1、3、6和12个月检查裸眼视力（UCVA），最佳矫正视力（BSCVA）、等效球镜（SE），并对数据进行分析比较。结果术后第1天UCVA达到1．0的比例SBK组较LASIK组低，但术后各随访时间点视力比较LASIK组和SBK组差异没有统计学意义（P〉0．05）。术后1d、7d、1个月时epi—LASIK组视力与LASIK组和SBK组相比差异有统计学意义（P〈0．05），术后3个月三组则差异无统计学意义（P〉0．05）；SBK组和LASIK组手术后1个月与手术前差别无统计学意义（P〉0．05）；Epi—LASIK手术后3月CS与手术前水平差异无统计学意义（P〉0．05）。角膜前表面像差手术前后三组差异无统计学意义（P〉O．05），角膜后表面像差LASIK组手术前后差异有统计学意义（P=0．000）。结论SBK手术矫正近视安全、有效及可预测性好；SBK手术可以与LASIK手术一样视力恢复快手术无痛苦，又可以和epi—LASIK手术一样极大地维持组织结构。Objective To evaluate the efficacy, predictability, stability, and safety of the surgical correction myopia by three refractive surgeons. Methods All cases were divided into two groups according to Mcrokeratoime, SBK group （sub-Bowman＇s keratomilensi）, LASIK group （Laser in situ keratomileusis） and epi-LASIK group （epipolis laser-insitu keratomilensis）. All cases were examined UCVA （uncorrected visual acuity）, BSCVA （best corrected visual acuity） preoperatively and post operation 1 day, 1 week, 1 month, 3, 6 and 12 months. Results The rate of eyes which UCVA higher than 1.0 was 90.2% in LASIK group, 91.4% in SBK group 1 day post operation, Which had no statistical difference between two groups during all following times （P 〉0.05）. The UCVA in epi-LASIK group was lower than the other two groups at 1 day, 1 week, 1 month, and the UCVA at 3 months had no statistical difference among three groups. The CS decreased early after surgery in LASIK and SBK, and achieved the preoperative level 1 month after surgery. The Z （4, 0） of the anterior corneal surface increased post surgery and had statistical difference among three groups. The Z （4, 0） of the posterior corneal surface increased post surgery and had statistical difference in LASIK group and had no statistical difference in SBK and Epi-LASIK group. Conclusions It is efficacy, predictability, safety and reliability to treatment myopia by SBK, the clinical effective of SBK preceded the Epi-LASIK and is similar with LASIK.

关 键 词：SBK LASIK epi—LASIK 近视 

分 类 号：R772[医药卫生—眼科]