个体化3D打印钛合金下颌骨植入体的设计制作与临床应用  

Design,Manufacture and Application of Individual Mandible Titanium Alloy Implant Based on Three Dimensional Printing

作　　者：张庆福 刘刚 刘国勤 

机构地区：[1]上海市解放军第四一一医院口腔专科中心,上海200081

出　　处：《口腔医学研究》2015年第1期48-51,共4页Journal of Oral Science Research

基　　金：南京军区医药卫生基金项目(编号:06MA06)

摘　　要：目的:通过钛合金3D打印技术的拓展,对个体化钛合金下颌骨植入体的设计、制作与临床应用进行探讨。方法:1)对1例单侧下颌骨体部与升支造釉细胞瘤患者,在手术前对下颌骨作薄层螺旋CT扫描,然后采用计算机辅助技术,进行下颌骨三维重建、模拟病变切除、镜像修复及植入体的设计,同时通过力学分析对植入体进行生物力学优化;2)将设计完善的下颌骨植入体数据输入钛合金3D打印设备,完成解剖形态个体化的下颌骨钛合金植入体制作;3)根据术前设计进行病变侧下颌骨切除,术中即刻将下颌骨植入体植入。结果:基于钛合金3D打印技术设计和制作的下颌骨植入体,在解剖形态上完全达到个体化三维仿真,与健侧下颌骨对称一致,缺损下颌骨的解剖形态即刻得到个体化修复重建。结论:钛合金3D打印技术使得解剖形态高度个体化仿真的下颌骨植入体的设计制作和临床应用成为现实,优化设计的钛合金下颌骨植入体力学性能优良,重量轻,制作精度高,为下颌骨节段性缺损的修复重建提供了一种理想的方法。Objective：To investigate the design,manufacture and application of individual titanium alloy mandible implant based on three dimensional printing of titanium alloy.Methods：A patient with large mandible body,angle and ramus ameloblastomas was given a spiral CT scanning.Based on the CT scanning,the pathological changed mandible was reconstructed,and after which simulated resection,individual mandible implant design and optimization was carried out.When the design of the implant was finished,the data of the implant was input into the three dimensional printing machine and the individual mandible implant was manufactured.During the operation,when the pathological mandible was removed,the mandible implant was accurately assembled immediately.Results：The titanium alloy mandible implant designed and manufactured based on three dimensional printing was highly individual anatomic emulation,and highly inosculated with healthy mandible.The shape and the function were renewed ideally.Conclusion：Three dimensional printing of titanium alloy made the design,manufacture and clinical application of highly individual anatomic emulated mandible implant realism.Optimized design could made the titanium alloy mandible implant has realistic biomechanical capability,light weight and right precision.

关 键 词：下颌骨缺损 3D打印 钛合金 下颌骨植入体 

分 类 号：R782.2[医药卫生—口腔医学]