近视眼角膜非球面参数分布特征  

Research on distribution characteristics of corneal asphericity of myopic eyes

作　　者：江秋若[1] 黄锦海[1] 李坚[1] 徐丹[1] 陈世豪[1] 王勤美[1] 

机构地区：[1]温州医科大学眼视光学院 温州医科大学附属眼视光医院,325027

出　　处：《中华眼视光学与视觉科学杂志》2015年第1期39-43,共5页Chinese Journal Of Optometry Ophthalmology And Visual Science

基　　金：国家自然科学基金（81300807）;浙江省医药卫生科技计划项目（2012KYB135）;浙江省教育厅科研项目（Y201223147）

摘　　要：目的 研究近视准分子激光人群术前角膜前后表面非球面参数（Q值）的分布特征,为临床诊疗提供理论基础.方法 前瞻性研究.应用基于Scheimpflug照相原理的Pentacam HR眼前节测量及分析系统对75例近视患者右眼进行测量,患者分为低度角膜散光组（前表面散光＜＋1.00 D）和中高度角膜散光组（前表面散光≥＋1.00 D）,系统分析角膜前后表面平均Q值分布特征,角膜中央不同角度范围Q值分布特征,上方、下方、鼻侧及颞侧半子午线上Q值分布特征.2组间比较采用独立样本t检验,各组内Q值间比较采用单因素方差分析.结果 该75例角膜中央30°范围平均Q值前表面为-0.17±0.09,后表面为-0.02±0.16.角膜前表面2组不同角度范围平均Q值均小于0,且2组对应角度范围内Q值间差异无统计学意义,2组内不同角度范围平均Q值间差异有统计学意义（F=6.340、9.963,P＜0.01）,2组Q20均大于Q30及Q25且差异具有统计学意义（P＜0.05）,Q30及Q25之间差异无统计学意义.角膜后表面Q30趋近于0,Q25及Q20均大于0,Q30＜Q25＜Q20,且差异均具有统计学意义（F=54.614,P＜0.01）.角膜前表面2组不同半子午线上平均Q值均为负且2组对应半子午线上平均Q值间差异无统计学意义,2组不同半子午线上平均Q值间差异有统计学意义（F=19.262、31.935,P＜0.01）.低度角膜散光组QN30小于Q130、QS30及QI30,且差异均具有统计学意义（P＜0.05）,QT30、QS30及QI30之间差异均无统计学意义（P＞0.05）.中高度角膜散光组QS30及Q130之间差异无统计学意义（P＞0.05）,QN30＜QT30且QN30及QT30小于QS30及Q130,差异均具有统计学意义（P＜0.05）.角膜后表面QS30趋近于0,QI30为正,QN30及QT30为负,不同半子午线上平均Q值间差异有统计学意义（F=31.750,P＜0.01）,其中QT30及QS30之间差异无统计学意义（P＞0.05）,QN30＜QT30且QS30＜QI30,差异均具有统计学意义（P＜0.05）.结论 近视人群角�Objective To evaluate the distribution characteristics of the asphericity （Q-value） of the corneal surfaces in a Chinese population who were candidates for excimer laser surgery; to provide some theoretical bases for clinical diagnosis and treatment.Methods This was a perspective study.Using the Pentacam HR measuring and analyzing system based on Scheimpflug photography,the right eyes of 75 Chinese myopes were evaluated for excimer laser surgery.Patients were divided into a low corneal astigmatism （〈＋1.00 D） group and a medium-high corneal astigmatism （≥＋1.00 D） group according to the anterior corneal surface astigmatism.The analysis was based on the distribution characteristics of the mean Q-values of both the anterior and posterior corneal surfaces and the distribution characteristics of the Q-value at different angles （20°,25° and 30°） and along different semi-meridians （superior,inferior,nasal and temporal）.Single factor analysis of variance was used to determine if there was a difference among Q-values within a particular group.The differences between the two groups were analyzed by an independent samples t-test.Results The mean Q-values of the 30° angle in Chinese myopes evaluated for excimer laser surgery were-0.17±0.09 and-0.02±0.16 on the anterior and posterior corneal surfaces,respectively.The mean Q-values of the anterior corneal surface at different angles were negative and there was no statistically significant difference between the low corneal astigmatism group and medium-high corneal astigmatism group.There was a significant difference between the Q-values of the 2 groups at different angles （F=6.340,9.963,P〈0.01）,and in both groups Q20 was significantly larger than Q30 and Q25 （P〈0.05） but there was no statistically significant difference between Q30 and Q25.The mean Q-values of the posterior corneal surface were positive at the 20° and 25° angles and approached zero at the 30° angle.Comparisons between the 3 angles showed statistically significant

关 键 词：角膜 非球面性 Scheimpflug照相技术 

分 类 号：R778.11[医药卫生—眼科]