原发性双侧乳腺癌的超声及病理分析  

Analysis of Ultrasonographic and Pathological Manifestations in Patients with Primary Bilateral Breast Cancer

作　　者：张萌璐 马步云[1] 

机构地区：[1]四川大学华西医院超声科,成都610041

出　　处：《华西医学》2015年第1期63-65,共3页West China Medical Journal

摘　　要：目的探讨原发性双侧乳腺癌的超声特征及病理表现。方法收集2001年1月-2009年4月24例经手术病理及临床证实的原发性双侧乳腺癌患者资料。其中双侧同时性乳腺癌患者9例,年龄41~60岁,平均47.3岁;双侧异时性乳腺癌患者15例,首癌诊断年龄33~61岁,平均43.2岁,第二癌诊断年龄38~69岁,平均49.1岁,首癌与第二癌间隔时间3~8年,平均5.9年。对其超声和病理资料进行回顾性分析。结果原发性双侧乳腺癌的分布部位以外上象限居多,多数肿瘤的边界不清楚,形态不规则,内部回声不均匀;而纵横径比值、后方回声衰减和钙化灶见于部分肿瘤;Adler血流分级以较高的Ⅱ和Ⅲ级为主。病理检查结果显示双侧同时性乳腺癌中浸润性导管癌17个,浸润性小叶癌1个;双侧异时性乳腺癌中浸润性导管癌27个,导管内癌2个,髓样癌1个。结论多数原发性双侧乳腺癌具有典型乳腺癌的超声征象,乳腺癌术后随访应建立在超声等影像学的基础上,超声导向下的穿刺活体组织检查可以提高双侧乳腺癌的检出率。Objective To explore the ultrasonographic and pathological manifestations of primary bilateral breast cancer （PBBC）. Methods The ultrasonographic and clinical manifestations of 24 patients with PBBC confirmed by surgical pathology and clinical examination between January 2001 and April 2009 were studied retrospectively. The study contained 9 bilateral synchronous breast cancer patients aged from 41 to 60 years old, averaging 47.3 years, and 15 bilateral asynchronous breast cancer patients. For patients with bilateral asynchronous breast cancer, the age on the first lesion diagnosis was between 33 to 61 years with an average of 43.2; the age on the second lesion diagnosis was from 38 to 69 years old averaging 49.1; and the interval time between the first and second lesion diagnosis was from 3 to 8 years, averaging 5.9 years. Results The site of PBBC was more located in upper outer quadrant. Most lesions had obscure boundary, irregular shape, and heterogeneous internal echo in ultrasonographic manifestation. The vertical and horizontal diameter ratio 〉 1, acoustic shadowing, and microcalcification occurred in some of the lesions. The bloodstream of the lesions were mainly Adler grade Ⅱ or Ⅲ . Conclusions Most PBBC has typical ultrasonographic manifestations. The follow-up of PBBC patients should be based on imaging such as ultrasonography. The biopsy guided by ultrasonography can elevate the detection rate of PBBC.

关 键 词：原发性双侧乳腺癌 超声检查 病理检查 

分 类 号：R737.9[医药卫生—肿瘤]