年龄及术前合并症对口腔癌患者术后并发症的影响  

Influence of age and preoperative complications on occurrence of postoperative complications in elderly patients with oral cancer

作　　者：肖瑞[1] 李华[1] 席庆[1] 鄂玲玲[1] 张艳芳[1] 欧龙[1] 曹均凯[1] 刘洪臣[1] 

机构地区：[1]解放军总医院口腔科,北京100853

出　　处：《解放军医学杂志》2015年第1期56-59,共4页Medical Journal of Chinese People's Liberation Army

基　　金：解放军总医院苗圃基金(12KMM28)~~

摘　　要：目的探讨老年口腔癌患者年龄及术前合并症等因素对术后并发症的影响。方法回顾性分析2014年1-7月解放军总医院口腔科收治的行手术治疗的106例口腔癌患者(老年口腔癌患者66例,非老年口腔癌患者40例)的资料,分析年龄及术前合并症与患者术后并发症的关系。结果老年口腔癌组术前高血压、心脏病、肺部疾病、贫血及多种合并症与非老年口腔癌组比较明显增高(P<0.05);但两组间术后并发症发生率差异无统计学意义。老年口腔癌组27例存在≥2种合并症的患者中14例(51.9%)术后发生并发症,与老年口腔癌组并发症的总体发生率(17例,25.8%)比较差异有统计学意义(P=0.0244)。非老年口腔癌组中,15例存在合并症的患者中术后有6例(40.0%)发生并发症,与老年口腔癌组并发症的总体发生率比较差异无统计学意义(P=0.4462)。糖尿病、肺部疾病、低蛋白血症和贫血等4种术前合并症均与无并发症的老年口腔癌组比较差异有统计学意义(P<0.05)。结论年龄不是老年口腔癌患者术后并发症的独立因素,糖尿病、肺部疾病、贫血、低蛋白血症等术前合并症是老年口腔癌患者术后发生并发症的高危因素。Objective To investigate the influence of age and preoperative complications on occurrence of postoperative complications in elderly patients with oral cancer. Methods The clinical data of 106 patients with oral cancer who had undergone surgical treatment in the General Hospital of PLA from Jan. to Jul. 2014 were retrospcetively analysed. Among them, 66 patients were over 60 years old, and 40 patients were under 60 years old. The relationship between age, preoperative complications and postoperative complications was analyzed. Results Complications including hypertension, heart disease, lung disease, anemia, etc. were significantly higher in patients of elderly group than in non-elderly group （P〈0.05）, but no significant difference was found in incidence of postoperative complications between two groups. Of 27 cases with more than 2 kinds of complications in elderly group, 14 （51.9%） suffered from postoperative complications, showing a significant difference （P=0.0244） compared with the overall incidence of postoperative complications in elderly group （17/66, 25.8%）. Of 15 patients with preoperative complications in non-elderly group, 6 （40.0%） suffered from postoperative complications, but no significant difference （P=0.4462） was found when compared with that of postoperative complications in elderly group. In elderly patients, the incidence of postoperative complications was significantly different between those with preoperative complications （diabetes, lung disease, hypoalbuminemia or anemia） and those without preoperative complications （P〈0.05）. Conclusion Age is not the independent risk factor for occurrence of postoperative complications, while some preoperative complications （such as diabetes mellitus, lung disease, hypoproteinemia and anemia） are the risk factors related to postoperative complications.

关 键 词：口腔肿瘤 老年人 术前合并症 手术后并发症 

分 类 号：R739.8[医药卫生—肿瘤]