肝衰竭患者临床预后判断研究进展  

Research progress in prediction of clinical outcome in patients with liver failure

作　　者：汤善宏[1,2] 曾维政[1] 蒋明德[1] 范泉水[2] 

机构地区：[1]成都军区总医院消化内科,成都610083 [2]成都军区疾病预防控制中心,成都610083

出　　处：《临床肝胆病杂志》2015年第1期135-138,共4页Journal of Clinical Hepatology

基　　金：成都军区"十二五"计划面上项目(C14036)

摘　　要：肝衰竭是指多种原因导致肝细胞合成、解毒、排泄和生物转化等功能严重障碍,出现以凝血功能障碍、黄疸、肝性脑病、腹水等为主要表现的一组临床症候群,由于肝衰竭疾病凶险,因此预后判断对于其诊治具有重要意义。近年来对于肝衰竭预后判定报道屡见不鲜,回顾了有关血清学及综合模型的研究及应用,为临床肝衰竭患者合理治疗提供参考。Liver failure is a clinical syndrome with severe disorders of liver cells for biosynthesis,detoxication,excretion,and biological transformation,which presents with coagulation disorders,jaundice,hepatic encephalopathy,and ascites.Liver failure progresses rapidly, so the prediction of clinical outcome is significant for the diagnosis and treatment.In recent years,there have been numerous reports on the prediction of clinical outcome in patients with liver failure.The study and application of serological and comprehensive models are reviewed, which provides a reference for the rational therapy for liver failure patients.

关 键 词：肝功能衰竭 预后 综述 

分 类 号：R575.3[医药卫生—消化系统]