薏苡茎甲醇提取物的抗氧化性研究  

Study on Antioxidant Effect of the Extracts of Methanol from Stem of Coix lachryma-jobi L.

作　　者：卢善善 黄挺章 李远辉[2] 黄莹[2] 马忠丽[2] 张照平[1] 黄锁义[3] 

机构地区：[1]右江民族医学院护理学院,广西百色533000 [2]右江民族医学院临床学院,广西百色533000 [3]右江民族医学院药学院,广西百色533000

出　　处：《中国野生植物资源》2015年第1期12-14,共3页Chinese Wild Plant Resources

基　　金：国家自然科学基金资助项目(81360684);广西自然科学基金资助项目(2011GXNSFA018046);广西中医药科技专项资助课题(GZKZ10-128);广西教育厅课题(201106LX425);广西中医药管理局课题(gzzc1047);广西医学科学实验中心开放基金专项资助项目(KFJJ2011-04)

摘　　要：目的:本文研究薏苡茎甲醇提取物的抗氧化作用。方法:以甲醇为溶剂提取;采用比色法测定薏苡茎甲醇提取物对DPPH·、O-2·两种自由基的清除作用以及还原Fe3+的能力。结果:薏苡茎甲醇提取物对两种自由基均有明显的清除作用;对Fe3+也具有较强的还原能力。结论:在一定范围内浓度与清除率存在明显的量效关系,当提取物浓度增加时,对DPPH·、O-2·两种自由基的清除作用随着增强;还原Fe3+能力也随薏苡茎提取物的浓度增加而增强。Objective： Study on antioxidant effect of the extracts of methanol from the stem of Coix lachryma-jobi L. Methods： The stem of Coix lachryma-jobi L. was extracted by methanol soaking. Clearance ability of the extracts of methanol on DPPH · and O-2· and the reduction of Fe3 ＋ability were measured with the spectrophotometry. Results： Extracts of stem of Coix lachryma-jobi L. had significant scavenging effect to two kinds of radicals,moreover it had strong ability of reduction to Fe3 ＋. Conclusion： In a certain rang,there was an obvious dose-effect relationship between concentration and clearance rate. When the concentration increases,the two kinds of free radical clearance rate and the reduction of Fe3 ＋ability increased.

关 键 词：薏苡茎 甲醇提取物 抗氧化性 

分 类 号：R282.71[医药卫生—中药学]