腹水超滤浓缩回输治疗肝硬化顽固性腹水60例  

Concentrated Ascites Reinfusion in Treatment of 60 Liver Cirrhosis Patients with Refractory Ascites

作　　者：刘杰[1] 赵书云[2] 龚丽娟[1] 曹建彪[1] 

机构地区：[1]北京军区总医院全军肝病治疗中心,北京100700 [2]北京军区总医院中医科,北京100700

出　　处：《解放军医药杂志》2015年第2期11-12,16,共3页Medical & Pharmaceutical Journal of Chinese People’s Liberation Army

基　　金：中国肝炎防治基金会王宝恩肝纤维化研究基金(XJS201302)

摘　　要：目的观察腹水超滤浓缩回输治疗肝硬化顽固性腹水的临床效果。方法对2011年11月—2013年12月北京军区总医院全军肝病治疗中心收治的肝硬化顽固性腹水60例,采用腹水超滤浓缩回输治疗,观察治疗前后的腹围、体重、尿量、肝肾功能、腹水检测、临床疗效和不良反应发生情况。结果 60例均顺利完成治疗。与治疗前比较,治疗后患者腹围减小、体重下降、尿量增多、血浆白蛋白升高,腹水经超滤浓缩后总蛋白和钠升高,钾和氯降低(P<0.05),总有效率为78.3%。7例出现低热自行缓解,2例发热和3例出现肝性脑病给予相应处理后好转。结论腹水超滤浓缩回输治疗肝硬化顽固性腹水安全、有效。Objective To observe clinical effect of concentrated ascites reinfusion in treatment of liver cirrhosis patients with refractory ascites. Methods A total of 60 liver cirrhosis patients with refractory ascites during November2011 and December were treated with concentrated ascites reinfusion,and the abdominal circumference,body weight,urine volume,hepatonephric function,ascites detection,clinical curative effect and adverse reactions before and after the treatment were observed. Results All the 60 patients successfully completed the treatment. Compared with those before the treatment,the values of abdominal circumference and body weight were decreased,while the values of urine output and plasma albumin after treatment were increased,and the total protein,potassium,sodium and chlorine levels after the concentrated ascites reinfusion were on the whole improved（ P〈0. 05）. The total effective rate was 78. 3%. Seven patients had low-grade fever but relieved by themselves,and symptoms of 2 patients with fever and 3 patients with hepatic encephalopathy improved after corresponding treatment. Conclusion The concentrated ascites reinfusion in treatment of liver cirrhosis patients with refractory ascites is safe and effective.

关 键 词：肝硬化 腹水 腹水浓缩回输 

分 类 号：R575.2[医药卫生—消化系统]