三阴型乳腺癌的MRI特征  

Characteristics of triple-negative breast cancer on MR imaging

作　　者：李艳玲[1] 李晓婷[1] 曹崑[1] 张晓鹏[1] 孙应实[1] 

机构地区：[1]北京大学临床肿瘤学院北京肿瘤医院暨北京市肿瘤防治研究所医学影像科,恶性肿瘤发病机制及转化研究教育部重点实验室,北京100142

出　　处：《中国医学影像技术》2015年第2期244-247,共4页Chinese Journal of Medical Imaging Technology

基　　金：首都卫生发展科研专项基金(2011-2015-02);北京市卫生系统高层次卫生技术人才学科骨干培养计划(2013-3-083);国家自然科学基金(81471640);北京市科学技术委员会:首都特色临床应用研究专项(Z121107001012115)

摘　　要：目的探讨三阴型乳腺癌(TNBC)的MRI(包括动态增强DCE及扩散加权成像DWI)特征。方法收集符合要求的病例入组,比较TNBC组与Luminal组的MR形态学、动态参数及DWI的ADC值的差异。结果 44例TNBC及183例Luminal型患者,TNBC组和Luminal B型组的形态学特征及DCE参数差异均无统计学意义,而两者的ADC值差异有统计学意义,TNBC组的ADC值较高(P=0.001)。结论 TNBC存在一定的DWI特征性。相对于Luminal型来说,TNBC倾向出现较高的ADC值。Objective To explore the characteristics of triple-negative breast cancer（TNBC）on MRI（including DCE-MRI and DWI）.Methods Patients meeting the criteria were recruited into the group,and comparison of difference was made between TNBC group and Luminal group in morphologic characteristics,dynamic parameters and ADC value.Results A total of 44 cases of TNBC and 183 cases of Luminal breast cancer patients were enrolled.There were no statistal difference in morphology characteristics and DCE parameter between two groups;however,ADC value in TNBC group was higher than that of Luminal group（P=0.001）.Conclusion TNBC shows certain characteristics on breast DWI.As to Luminal type,it tends to appear a higher ADC value.

关 键 词：乳腺肿瘤 磁共振成像 三阴型 

分 类 号：R737.9[医药卫生—肿瘤] R445.2[医药卫生—临床医学]