不同类型青光眼患者前部巩膜厚度与眼部生物学参数的相关性  

Correlation between anterior sclera thickness and other ocular biological parameters in patients with different types of glaucoma

作　　者：郑彪[1] 蔡艳霞[1] 柯毅[1] 

机构地区：[1]广东医学院附属医院眼科,广东省湛江市524001

出　　处：《眼科新进展》2015年第2期177-179,共3页Recent Advances in Ophthalmology

摘　　要：目的探讨不同类型青光眼患者前部巩膜厚度(anterior sclera thickness,AST)与眼部生物学参数的相关性。方法选取2012年1月至2013年6月我院收治的青光眼患者80例(80眼),其中原发性闭角型青光眼(primary angle-closure glaucoma,PACG)38例,原发性开角型青光眼(primary open angle glaucoma,POAG)42例,另选取于我院同期健康体检的健康无眼疾者40例(40眼)作为对照,采用超声生物显微镜(ultrasound biomicroscopy,UBM)对AST进行检测,DGH-1000型超声角膜测厚仪测量中央角膜厚度(central corneal thickness,CCT),同时采用眼科A/B超对眼轴长度(axial length,AL)进行测量,对测量结果进行比较分析。结果 POAG组、PACG组AST与对照组相比,差异均无统计学意义(均为P>0.05);POAG组AST与PACG组相比,差异无统计学意义(P>0.05)。POAG组、PACG组CCT与对照组相比,差异均有统计学意义(均为P<0.05),POAG组、PACG组CCT均大于对照组;POAG组CCT与PACG组相比,差异有统计学意义(P<0.05),POAG组CCT大于PACG组。POAG组、PACG组AL与对照组相比,差异均有统计学意义(均为P<0.05),POAG组、PACG组AL均小于对照组;POAG组AL与PACG组相比,差异有统计学意义(P>0.05),POAG组AL小于PACG组。POAG组CCT值与AST值间呈线性正相关(r=0.544,P=0.018),但PACG组CCT值与AST值间均未发现线性相关(r=-12.345,P=0.058);两组AL与AST均无相关性。结论不同类型青光眼患者的CCT有一定的差异,但各型青光眼患者AST无明显差异,POAG患者的CCT与AST可能存在一定的正相关。Objective To discuss the correlation between anterior sclera thick- ness （AST） and other ocular biological parameters in patients with different types of glaucoma. Methods Eighty patients （ 80 eyes） with different types of glaucoma in our hospital form January 2012 to June 2013 were enrolled,including 38 cases with primary angle-closure glaucoma （PACG） and 42 cases with primary open-angle glaucoma （ PO- AG）, and other 40 healthy cases （40 eyes）were chosen as controls, the AST was detec- ted by ultrasound biomicroscopy,the central corneal thickness （CCT）was measured by DGH-1000 corneal ultrasound pachymeter,and the axis length （AL）was also measured by A/B ultrasound, the results were compared and analyzed. Results There was no statistical difference in AST between PACG group, POAG group and control group （ all P 〉 0.05 ）, no difference was found between POAG group and PCAG group （P 〉 0.05 ）, but there were statistical differences in CCT between PACG group, POAG group and control group （ all P 〈 0.05 ）, and there was statistical difference in CCT between PACG group and POAG group （P 〈 0.05 ）. There were statistical differences in AL between PACG group, POAG group and control group （ all P 〈 0.05 ）, and there was statistical difference between PACG group and POAG group （P 〈 0.05 ）. In POAG group, CCT and AST value showed a linear positive correlation（ r = 0. 544 ,P = 0. 018 ）, but in the PACG group CCT value and AST value are not linear correlation （r = - 12.345 ,P = 0.058）. AL and AST of two groups had no correlation. Conclusion In patients with different types of glau- coma, CCT have some differences, but no significant difference in AST, CCT and AST in patients with POAG may be positive correlated.

关 键 词：青光眼 前部巩膜厚度 中央角膜厚度 眼轴长度 相关性 

分 类 号：R778.11[医药卫生—眼科]