131名护士职业应激与唾液α淀粉酶的相关分析  

Correlation between nurse occupational stress and salivary alpha-amylase： an analysis of 131 cases

作　　者：刘留留 田宏迩[1] 詹永国[1] 张庆东[2] 朱新云[2] 曹丽丽[1] 张虎[1] 

机构地区：[1]东南大学公共卫生学院,南京,210009 [2]江苏省扬中市疾病预防控制中心

出　　处：《中华劳动卫生职业病杂志》2015年第2期121-124,共4页Chinese Journal of Industrial Hygiene and Occupational Diseases

基　　金：教育部人文社会科学研究规划基金（14YJA840012）

摘　　要：目的 探讨护士职业应激与唾液α淀粉酶（SAA）的关系.方法 对131名在职护士进行职业应激程度评定,采用酶联免疫吸附试验（ELISA）测定其唾液中α淀粉酶活力.结果 不同年龄、工龄护士SAA活力有差异（P＜0.05）,＞35岁组基线活力、工作期活力、恢复期活力、平均活力均低于≤30岁组,差异有统计学意义（P＜0.05）;10～15年组、＞15年组工作期活力均低于≤10年组（P＜0.05）;不同学历间SAA活力差异无统计学意义（P＞0.05）.工作需求高评分组的工作期SAA活力高于低评分组（P＜0.05）,角色冲突与模糊高评分组的基线SAA活力高于低评分组（P＜0.05）;基线SAA活力与工作负荷、角色冲突、角色模糊呈正相关（P＜0.05）;工作期SAA活力与任务控制、决策控制、技术利用度呈负相关（P＜0.05）,与定量负荷、负荷变化、工作单调性、工作负荷呈正相关（P＜0.05）;恢复期SAA与任务控制、决策控制、资源控制、技术利用度呈负相关（P＜0.01）;平均SAA活力与任务控制、决策控制、资源控制、技术利用度、参与决策机会、提升机会呈负相关（P＜0.05）,与定量负荷、负荷变化、工作负荷、角色模糊呈正相关（P＜0.05）.结论 131名护士职业应激与唾液α淀粉酶活力有相关性,可作为职业应激识别与评价的客观生物标志物.Objective To explore the relationship between nurse occupational stress and salivary alphaamylase （SAA）.Methods Evaluation of occupational stress was conducted in 131 nurses.The activity of SAA was determined using enzyme-linked immunosorbent assay （ELISA）.Results The activity of SAA in nurses varied with age and working years.The baseline,work period,recovery,average activities of 〉35 age group were less than those of ≤ 30 age group; work period,recovery,average activities of≤ 10 years group were higher than other two groups; theres was no statistical difference between SAA vitalities of different degree groups （P〉0.05）.In nurses with high scores for job demands,the activity of SAA in working period was significantly higher than that in nurses with low scores （P〈0.05）.The baseline SAA activity in nurses with high scores for role conflict and ambiguity was significantly higher than that in nurses with low scores （P〈0.05）.The baseline SAA activity was positively correlated with workload,role conflict,and role ambiguity （P〈0.05）.The activity of SAA in working period was negatively correlated with task control,decision control,and technology utilization （P〈0.05）,and was positively correlated with quantitative load,load change,work monotony,and workload （P〈0.05）.The activity of SAA in recovery period was negatively correlated with task control,decision control,resource control,and technology utilization （P〈0.01）.The average activity of SAA was negatively correlated with task control,decision control,resource control,technology utilization,opportunity for participating in decision-making,and promotion （P〈0.05）,and was positively correlated with quantitative load,load change,workload,and role ambiguity （P〈0.05）.Conclusion The occupational stress in 131 nurses is correlated with the activity of SAA,which can be used as an objective biomarker for identification and evaluation of occupational stress.

关 键 词：护士 应激 Α淀粉酶 唾液 

分 类 号：R47[医药卫生—护理学]