精氨酸对仔猪肠道机械屏障的影响及相关机理  

Effect of Arginine on Piglet Intestinal Mechanical Barrier and Related Mechanism

作　　者：姜海龙[1] 秦贵信[1] 车东升[1] 谷琳琳[1] 张海全[1] 赵金波 

机构地区：[1]吉林农业大学动物科学技术学院,长春130118 [2]大兴安岭地区农业林业科学研究院,大兴安岭165000

出　　处：《吉林农业大学学报》2015年第1期83-87,共5页Journal of Jilin Agricultural University

基　　金：国家星火计划项目(2012GA660001);吉林省世行贷款农产品质量安全项目(2011-Y04)

摘　　要：肠道屏障功能具有抵御病原菌和毒素入侵机体的能力,肠道机械屏障是其中最重要的一道屏障。精氨酸可以直接或间接影响肠道机械屏障,文章从精氨酸对猪肠道黏膜生长、绒毛高、细胞生长、肠道通透性等方面简述精氨酸在仔猪肠道屏障功能中的重要作用;并从m TOR信号通路及NO途径等方面对精氨酸影响仔猪肠道机械屏障的机理进行阐述,为深入认识精氨酸在肠道屏障中的作用提供参考。Intestinal barriers have the ability to resist invasion of pathogenic bacteria and toxin into the body and intestinal mechanical barrier is one of the most important barriers. Arginine can directly or indirectly affect intestinal mechanical barrier. This paper briefly discusses the important role of arginine in piglet intestinal barrier function from the perspectives of intestine mucosa growth,villus height,cell growth and intestinal permeability. It also explicates the effects of arginine on mechanism of piglet intestinal mechanical barrier from the perspectives of m TOR signal pathway and NO way.The study provides reference for further understanding the role of arginine in intestinal barrier.

关 键 词：肠道屏障 精氨酸 肠道黏膜 通透性 MTOR 

分 类 号：S828.5[农业科学—畜牧学]