supported by the National Natural Science Foundation of China(Nos.81920108017 and 82130036);the Key Research and Development Program of Jiangsu Province of China(No.BE2020620);Jiangsu Province Key Medical Discipline(No.ZDXKA2016020)。
Microglia,the resident immune cells in the central nervous system(CNS),rapidly transition from a resting to an active state in the acute phase of ischemic brain injury.This active state mediates a pro-inflammatory res...
supported by the National Natural Science Foundation of China (No.81572447,31871427,32260173);Zhongnan Hospital-Taikang Medical School (School of Basic Medical Sciences)of Wuhan University Joint Foundation (No.JCZN2022010);supported by the intramural program of Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD),National Institutes of Health (NIH),USA.
Sex-determining region Y-box protein 3(SOX3)is a member of the SoxB1 transcription factors subfamily including SOX1 and sox2,first identified based on homology to the high mobility box.1 The oncogenic potential of the...
Smith-Kingsmore syndrome(SKS)is a very rare dominantly inherited disorder caused by a gain-of-function mutation in MTOR(mechanistic target of rapamycin).1,2 It is typically characterized by megalencephaly,developmenta...