游离前臂皮瓣联合H-ADM修复口腔肿瘤术后组织缺损的研究  

Study on Reconstruction of Postoperative Tissue Defects of Oral Tumor by Free Forearm Flap Combined with Heterogeneous Acellular Dermal Matrix

作　　者：居国平[1] 董煜[1] 高凤山[1] 刘阿贵[1] 赵健[1] 

机构地区：[1]江南大学附属医院口腔科,江苏无锡214062

出　　处：《临床医学工程》2014年第10期1289-1290,共2页Clinical Medicine & Engineering

摘　　要：目的观察前臂游离皮瓣联合异种脱细胞真皮基质(H-ADM)修复口腔肿瘤术后组织缺损的临床效果。方法 36例口腔肿瘤患者随机分为观察组和对照组各18例,对照组采用游离前臂皮瓣修复术后组织缺损,观察组采用游离前臂皮瓣联合H-ADM修复术后组织缺损。比较两组术后皮瓣存活率、语音功能、吞咽功能及术后供区恢复情况。结果观察组皮瓣存活率为100.00%,优于对照组的66.67%;观察组语音功能、吞咽功能以及供区恢复情况均优于对照组,所有差异均具有统计学意义(P<0.05)。结论应用游离前臂皮瓣联合H-ADM修复口腔肿瘤术后组织缺损是较为理想的方法,可恢复和改善患者的外形和生理功能,保持口腔和舌的基本功能,有效提高患者的生存质量。Objective To observe the clinical effect of free forearm flap combined with heterogeneous acellular dermal matrix （H-ADM） in reconstructing postoperative tissue defects of oral tumor. Methods 36 cases of patients with oral tumor were selected and randomly divided into observation group and control group, with 18 cases in each group. The control group was given free forearm flap, the observation group was given free forearm flap combined with H-ADM. The flap survival rate, voice function, swallowing function and postoperative recovery of supply area were compared. Results The flap survival rate of the observation group was 100.00%, better than 66.67%of the control group;and the voice function, swallowing function and postoperative recovery of supply area of the observation group were better than those of the control group, with significant difference （P 〈0.05）. Conclusions The application of free forearm flap combined with H-ADM is an ideal method to repair postoperative tissue defects of oral tumor, which will recover and improve patients＆#39; appearance and physiological functions, maintain the basic functions of mouth and tongue and effectively improve patients＆#39; quality of life.

关 键 词：前臂皮瓣 异种脱细胞真皮基质 口腔肿瘤 

分 类 号：R739.8[医药卫生—肿瘤]