青岛地区450名医院放射工作人员外周血淋巴细胞微核分析  

Peripheral blood lymphocytes micronucleus analysis of 450 hospital radiation workers in Qingdao area

作　　者：孙冰梅 王淑惠 宋学术 

机构地区：[1]青岛市中心医院,山东青岛266042

出　　处：《医学检验与临床》2014年第3期41-43,共3页Medical Laboratory Science and Clinics

摘　　要：目的：为了解青岛地区医院放射工作人员的淋巴细胞微核率与非接触放射线健康人群的微核率是否有统计学差异，为放射工作人员的辐射防护提供依据。方法：采用外周血淋巴细胞培养法进行微核检测，用x2检验对青岛地区450名医院放射工作人员和70名非接触放射线人员、男女性别及放射诊断、放射治疗、介入治疗和核医学四个工种之间比较进行统计分析。结果：医院从事放射工作人员的淋巴细胞微核率和微核细胞率显著高于对照组,差异均有统计学意义（x2值分别为3.8809，3.9286； P〈0.05）。男女性别及从事放射诊断、放射治疗、介入治疗和核医学工作人员的淋巴细胞微核率和微核细胞率之间的差别均无统计学意义。结论：医院放射工作人员在日常工作中接触到了要高于自然本底的长期低剂量电离辐射，并引起自身遗传物质一定损伤,有效的防护措施能够降低辐射损伤。To investigate the statistical variance of micronucleus of peripheral blood lymphocytes between radiation group workers and control group workers in Qingdao area,and provide scientific evidence for professional health protection.Methods：The conventional culture method for lymphocytes and x2 test were used to analyze the micronucleus rates and micronucleated lymphocyte rates between 450 radiation group workers and 70 control group workers,between males and females,between radiodiagnosis,radiotherapy, interventional therapy and nuclear medicine.Results： The micronucleus rates and micronucleated lymphocyte rates in radiation group workers were higher than control group workers.The difference was significant （x2＊ =3.8809 x2＊＊=3.9286 P＆lt;0.05）.No significant difference was found between males and females,also between radiodiagnosis,radiotherapy, interventional therapy and nuclear medicine.Conclusions：Radiation group workers in hospital receive a long low-dose of ionizing radiation damage higher than natural background.This radiation damage can cause genetic material change. Effective safeguard measures could reduce the radiation damage.

关 键 词：放射工作人员 淋巴细胞 微核 

分 类 号：R394[医药卫生—医学遗传学]