显微外科手术不同入路治疗鞍结节脑膜瘤的临床分析  

Clinical analysis of saddle nodules meningiomas using micro-surgery treatment of different approaches

作　　者：邹坤良 陈忠[1] 蔡洪[1] 刘谊[1] 

机构地区：[1]四川省达州市中心医院,达州635000

出　　处：《中国肿瘤临床与康复》2015年第2期200-201,共2页Chinese Journal of Clinical Oncology and Rehabilitation

摘　　要：目的分析显微外科手术不同入路治疗鞍结节脑膜瘤的临床效果。方法 150例鞍结节脑膜瘤患者按不同手术入路分为治疗组(采用经纵裂入路显微切除术治疗)和对照组(采用额下入路显微切除术治疗),每组75例,比较两组患者临床切除总有效率、治疗前后格拉斯哥昏迷(GCS)评分和并发症发生率。结果治疗组患者临床切除有效率为92.0%,对照组为89.3%,差异无统计学意义(P>0.05)。两组患者手术前GCS评分的差异无统计学意义(P>0.05)。两组患者治疗后GCS评分均明显优于治疗前,且治疗组更加优于对照组,差异有统计学意义(P<0.05)。治疗组患者并发症发生率为4.0%,明显低于对照组患者的20.0%(P<0.05)。结论经纵裂入路显微切除术在治疗鞍结节脑膜瘤疾病临床上效果显著,可明显降低对患者带来的损伤和并发症发生率,促进患者早日康复。Objective To evaluate the clinical effects of tuberculum sellae meningiomas using microsurgical treatment. Methods One hundred and fifty cases of tuberculum sellae meningioma patients from Dazhou Central Hospital were enrolled in the study,and were divided into the treatment group（ via transcallosal approach microsurgery treatment） and the control group（ via subfrontal approach microsurgery treatment）,according to different approaches. Related clinical effects,including total efficiency,Glasgow Coma（ GCS） score and complications,were compared between the two groups. Results The effectively removed rate of the treatment group patients were 92. 0%,the control group 89. 3%,and there was great significance between the two groups（ P〉0. 05）; The GCS scores of two groups have great significance（ P〉0. 05）; after treatment,GCS score was both significantly higher than that before treatment,and GCS score of the treatment group were significantly better than that of the control group（ P〈0. 05）; the incidence rate of the treatment group（ 4. 0%） was significantly lower than that of the control group（ 20. 0%）（ P〈0. 05）. Conclusion The transcallosal microsurgery in the treatment of tuberculum sellae meningioma disease shows clinically significant effect,which can significantly reduce the incidence of injury and complications of the patients,and promote early rehabilitation of patients.

关 键 词：鞍结节脑膜瘤 显微外科手术 不同入路 治疗结果 

分 类 号：R739.45[医药卫生—肿瘤]