中药有效成分及单体抗菌作用机制的研究进展  

The antibacterial effects of herb monomers: research advances

作　　者：阮贤妹[1,2] 史道华[2,3] 

机构地区：[1]福建医科大学附属福州市第一医院,福建福州350009 [2]福建医科大学药学院,福建福州350108 [3]福建省妇幼保健院药剂科,福建福州350001

出　　处：《中国微生态学杂志》2015年第2期244-248,共5页Chinese Journal of Microecology

基　　金：福建省福州市卫生局立项课题(2014-S-w4)

摘　　要：目前全球面临耐药形势严峻的挑战,更迫切寻找新的结构和新的作用机制的药物。许多中药具有抑菌或潜在抗感染作用,本研究收集整理国内外相关文献,对中药有效成分及单体抗菌的生物活性及机制方面作一综述,为中药单体在抗感染应用提供理论依据,加快中药单体抗感染的开发利用。The whole world is facing a severe challenge of drug resistance nowadays with more urgent need to find new structures and drugs with new mechanisms of action. Many traditional Chinese medicines have antibacterial or potential anti-inflammatory effects. This paper reviewed the relevant literatures on the biological activity and mechanisms of active ingredients and antibacterial monomers of traditional Chinese medicines,so as to provide a theoretical basis for the application of these anti-infective monomers,and promote the development of anti-infective herbal monomers

关 键 词：中药单体 抗菌机制 研究进展 

分 类 号：R285.5[医药卫生—中药学]