高龄老年患者轻度认知功能障碍的危险因素分析  

Risk factors of the very old patients with mild cognitive impairment

作　　者：邢云利[1] 孙颖[1] 王翠英[1] 唐梅[1] 黄樱硕[1] 马清[1] 

机构地区：[1]首都医科大学附属北京友谊医院医疗保健中心,北京100050

出　　处：《临床和实验医学杂志》2015年第3期196-199,共4页Journal of Clinical and Experimental Medicine

基　　金：首都医科大学基础和临床科研合作基金资助项目(编号:13JK57);北京市保健科研课题(京09-02)

摘　　要：目的探讨高龄老年患者轻度认知功能障碍的危险因素。方法入选111例老年科住院的高龄老年(年龄≥80岁)患者,根据简易精神状态量表(MMSE)水平,分为轻度认知功能障碍组(MCI组)和对照组,比较两组间在文化程度、高血压、糖尿病、高脂血症等方面的差异,发现影响高龄老年轻度认知功能障碍的危险因素。结果有66例患者存在MCI,占59.55%。大专及以上学历的高龄老人MCI发生率明显低于小学以下学历(28.1%比56.2%,P<0.05);MCI组高脂血症的发生率、总胆固醇(CHO)、低密度脂蛋白(LDL-C)水平明显高于对照组(P<0.05)。两组间高血压、糖尿病患病率无显著差异(P>0.05)。结论文化程度以及血脂水平与高龄老人轻度认知功能障碍高度相关。Objective The aim of this study was to investigate the correlation factors of mild cognitive impairment（ MCI） in the very old patients. Methods In this study,111 subjects were selected. according to Minimental State Examinati（ MMSE）,the patients were divided into MCI group and control group. And schooling,cardio- vascular risk factors such as hypertension,diabetes mellitus,and hyperlipemia were analyzed. Results According to the results,66 cases（ 59. 5%） suffered from MCI（ MMSE≥24）. Factors such as schooling,cholesterol（ CHO）,and low density lipoprotein cholesterol（ LDL- C） are of significant relationship with MMSE score（ P 0. 05）. Conclusion Schooling and hyperlipemia are highly correlated with MCI in the very old patients.

关 键 词：高龄老年 轻度认知功能障碍 危险因素 

分 类 号：R749.16[医药卫生—神经病学与精神病学]