黛力新对功能性消化不良患者治疗后焦虑和抑郁的改善作用  

Deanxit improves anxiety and depression in patients with functional dyspepsia

作　　者：郭秋霞[1] 彭娜[1] 吕飞[1] 姜齐宏[1] 

机构地区：[1]华中科技大学同济医学院附属普爱医院消化内科,湖北省武汉市430034

出　　处：《世界华人消化杂志》2015年第2期324-327,共4页World Chinese Journal of Digestology

摘　　要：目的:探讨氟哌噻吨美利曲辛片(黛力新)治疗功能性消化不良(functional dyspepsia,FD)的临床效果,为FD的临床治疗提供参考.方法:将华中科技大学同济医学院附属普爱医院2012-11/2014-05收治的110例FD患者随机分为观察组和对照组,每组55例,两组患者均给予常规基础治疗,观察组患者在常规治疗的基础上给予氟哌噻吨美利曲辛片口服治疗,对两组患者治疗后的对治疗的满意度、心理状态、临床效果进行比较和分析.结果:经治疗,观察组患者对治疗的满意度为92.7%,对照组患者对治疗的满意度为83.6%,比较两组间差异具有统计学意义(P<0.05).观察组患者焦虑自评量表(self-rating anxietyscale,SAS)评分、抑郁自评量表(self-rating depression scale,SDS)评分显著低于对照组(P<0.05);观察组治疗总有效率为85.45%对照组治疗总有效率为54.55%,两组患者治疗总有效率的比较差异具有统计学意义(P<0.05).结论:在常规治疗的基础上加用氟哌噻吨美利曲辛片治疗FD可有效减轻患者的情绪障碍,提高治疗有效率,值得临床推广.AIM： To assess the clinical effects of flupentixol and melitracen tablets（Deanxit） in the treatment of functional dyspepsia（FD）. METHODS： One hundred and ten patients with FD treated at our hospital from November2012 to May 2014 were randomly divided into either an observation group or a control group,with 55 cases in each group. The control group was given conventional basic therapy, and the observation group was given Deanxit on the basis of conventional therapy. Treatment satisfaction, mental status, and clinical results were compared for the two groups. RESULTS： After treatment, the observationgroup had a significantly higher rate of patient satisfaction than the control group with（92.7% vs 83.6%, P〈 0.05）. Self-rating anxiety scale（SAS） score and self-rating depression scale（SDS） score were significantly lower in the observation group than in the control group（P 〈0.05）. The total effective rate was significantly higher in the observation group than in the control group（85.45% vs 54.55%, P〈 0.05）.CONCLUSION ： Deanxit can effectively improves anxiety and depression in patients with FD.

关 键 词：氟哌噻吨美利曲辛片 功能性消化不良 治疗效果 

分 类 号：R57[医药卫生—消化系统]