经皮胆道射频消融治疗恶性黄疸的近期疗效  

Short-term effects of percutaneous intraductal radiofrequency ablation in patients with malignant jaundice

作　　者：申淑群[1] 张一军[1] 杨业发[1] 葛乃建[1] 梁军[1] 伍路[1] 于晓河[1] 石志勇[1] 吴孟超[1] 

机构地区：[1]第二军医大学东方肝胆外科医院微创介入中心,上海200438

出　　处：《实用放射学杂志》2015年第2期284-286,共3页Journal of Practical Radiology

摘　　要：目的：探讨经皮肝穿刺胆道射频消融联合支架植入术治疗恶性胆道梗阻引起的黄疸的安全性和有效性。方法回顾性收集18例行经皮肝穿刺胆道射频消融联合金属支架植入术的恶性胆道梗阻患者的临床资料。分析近期的疗效及并发症。结果经联合治疗后2 d,患者除白蛋白下降外,其他主要肝功能指标均显著改善,术后1月肝功能进一步改善,白蛋白升至治疗前水平。18例患者均未发生肝功能不全,无患者在30 d 内死亡。严重并发症中,胆管穿孔0例（0.0%）,胆漏1例（5.5%）,出血1例（5.5%）,术后胰腺炎0例（0.0%）；轻微并发症中,胆道感染3例（16.7%）,疼痛7例（38.9%）,呕吐3例（16.7%）。结论经皮肝穿刺胆管内射频消融联合支架植入术治疗恶性胆道梗阻是安全有效的。Objective To investigate the safety and efficacy of percutaneous intraductal radiofrequency ablation in combination with stent implantation for treatment of jaundice caused by biliary malignance.Methods The clinical data of malignant biliary ob-struction in 18 patients were collected retrospectively who were treated by percutaneous intraductal radiofrequency ablation in combi-nation with stent implantation.Results On two days after combined therapy,except for the decreased albumin,other major indica-tors of liver function were significantly recovered.At 1 month after therapy,the liver function further improved with normal level of albumin.No liver function insufficiency occurred in all patients,and no patient died within 30 days.Few serious complications inclu-ding bile leakage in 1 （5.5%）and hemorrhage in 1 （5.5%）and some slight complications including biliary tract infection in 3 （1 6.7%）,pain in 7 （38.9%）and vomit in 3 （1 6.7%）were observed.Conclusion Percutaneous transhepatic radiofrequency ablation combined with stent implantation is a safe and effective treatment for malignant biliary obstruction.

关 键 词：经皮肝穿刺胆道引流 射频消融 支架植入术 恶性胆道梗阻 

分 类 号：R575[医药卫生—消化系统] R815[医药卫生—内科学]