阿尔茨海默病诊断标准的演变  

The evolution of criteria for the diagnosis of Alzheimer's disease

作　　者：王晓妮[1] 唐毅[1] 韩璎[1] 

机构地区：[1]首都医科大学宣武医院神经内科,北京100053

出　　处：《医学研究生学报》2015年第2期195-198,共4页Journal of Medical Postgraduates

基　　金：国家自然科学基金(30970823;31371007);北京市科技计划课题(Z131100006813022)

摘　　要：阿尔茨海默病(Alzheimer's disease,AD)是老年痴呆最常见的病因,随着人口老龄化程度加剧,AD患病率也逐年增加,给社会和个人带来极大负担,早期诊断AD已成为当今研究的热点。文中将从最早期的AD痴呆诊断标准解析,逐渐过度到目前最新的AD临床前期主观认知下降的研究框架,试图为早期诊断AD提供新思路。Alzheimer＇s disease（ AD） is the most common disease leading to dementia. With aging of the population,the morbidity of AD is increasing significantly,which brings serious burden personally and socially. So the early diagnosis of AD has become the hotspot in the current research field. In order to highlight new ideas for the early diagnosis of AD,the current review will analyze from the first international diagnostic criteria for AD dementia to the latest conceptual framework for research on subjective cognitive decline in preclinical Alzheimer＇s disease.

关 键 词：阿尔茨海默病 主观认知下降 早期诊断 诊断标准 生物标记物 

分 类 号：R749.1[医药卫生—神经病学与精神病学]