即刻种植过程中种植体周围炎动物模型的建立  

Establishment of animal model with peri-implantitis after immediate implantation in rabbits

作　　者：沈兰花[1] 孟玲娜[1] 王鑫[1] 姜辉[1] 王珊珊[1] 

机构地区：[1]黑龙江省医院南岗院区口腔科,黑龙江哈尔滨150001

出　　处：《上海口腔医学》2015年第1期37-40,共4页Shanghai Journal of Stomatology

基　　金：黑龙江省卫生厅科研课题(2010-453)~~

摘　　要：目的 :建立即刻种植过程中种植体周围炎动物实验模型,利用Micro-CT观察种植体周围炎发展过程中的骨缺损特性。方法:在12只哈尔滨长耳白兔双侧下颌第一前牙即刻植入种植体,4周后,采用丝线拴结法在左下颌第一前牙诱发种植体周围炎,右下颌第一前牙作为对照,通过Micro-CT观察不同时期种植体周围炎导致的骨缺损状况。结果:丝线拴结法可以较好地诱发出即刻种植体周围炎,随着种植体周围炎的逐渐发展,种植体与骨之间无法达到良好结合,骨缺损逐渐产生并不断扩大,最后形成典型的"V"形骨缺损。结论:建立的即刻种植体周围炎动物模型简便有效,可为种植体周围炎的相关研究提供重要参考。PURPOSE： To establish animal model with peri-implantitis after immediate implantation and study bone defect characteristics by Micro-CT. METHODS： Implants were immediately planted in the first mandibular anterior tooth of 12 rabbits. Silk ligatures were placed around one side of the implants to induce peri-implantitis. Micro-CT was used to evaluate bone defect at different periods after implantation. RESULTS： Silk ligatures around the implants were effective to induce peri-implantitis. With the development of peri-implantitis, implants can not be well integrated with bone. Bone defect was gradually produced and then aggravated, and finally formed typical ＂V-type＂ bone defect. CONCLUSIONS：The establishment of animal model with peri-implantitis is simple and effective, which provides important references for relative studies in the field of peri-implantitis.

关 键 词：种植体周围炎 即刻种植 动物模型 兔 

分 类 号：R783.6[医药卫生—口腔医学] R-332[医药卫生—临床医学]