躯体形式障碍患者认知功能的影响因素分析  

Influencing factors analysis of cognitive functions in patients with somatoform disorders

作　　者：吴小霞[1] 谢国军[1] 罗伟森[1] 邓文[1] 赵长江[1] 黎雪松[1] 

机构地区：[1]广东省佛山市第三人民医院,528041

出　　处：《四川精神卫生》2015年第1期22-25,共4页Sichuan Mental Health

基　　金：广东省医学科研基金项目(A2010603)

摘　　要：目的探讨躯体形式障碍患者认知功能的影响因素。方法收集符合《精神障碍诊断与统计手册（第4版）》（DSM-IV）“躯体形式障碍”诊断标准的患者120例（研究组）及其一般人口学资料，并对患者进行瑞文标准推理测验（RSPM）、数字广度（DSP）与数字符号（DSY）测验以评估其认知功能，同时进行事件相关电位P300检测和艾森克人格问卷（EPQ）测试。选取60例正常健康者作为对照组。结果研究组的瑞文推理分数、数字广度分数、数字符号分数均低于对照组；N1、P2、P3潜伏期较对照组延长，NlN2、N2P2、P2P3波幅低于对照组，差异有统计学意义（P〈0．05或0．01）。性别与RSPM、DSY呈正相关（r=0．452、0．369，P〈0．01）；年龄、EPQ神经质因子均与RSPM、DSP、DSY呈负相关；受教育程度、婚姻状况、N2潜伏期、P2P3波幅均与DSP呈正相关（r=0．302～0．481，P〈0．01）；经济状况、Nl潜伏期均与RSPM、DSP、DSY呈正相关；家庭关系、EPQ精神质因子均与DSP、DSY呈负相关；心理因素、病程及疾病亚型与认知功能无相关性；EPQ内外向因子、NlN2波幅均与RSPM、DSP呈负相关；EPQ人格说谎因子与RSPM、DSY呈负相关（r=-0．570、-0．195，P〈0．05或0．01）；P2潜伏期与DSY呈正相关（r=0．261，P〈0．05）；P3潜伏期与DSP呈负相关（r=-0．237，P〈0．05）；N2P2波幅与RSPM、DSP负相关（r=-0．220、-0．293，P〈0．05或0．01）。结论躯体形式障碍患者认知功能的影响因素包括性别、年龄、受教育程度、婚姻状况、经济状况、家庭关状况系、人格特质、P300电位，而心理因素、病程、疾病亚型对认知功能没有影响。Objective To explore the influencing factors of cognitive functions in patients with somatoform disorders. Methods Collected general data of 120 cases of patients with somatoform disorders meeted with diagnosis standard of Diagnostic and Statistical Manual of Mental Disorders Fourth edition( DSM-IV) using Random Number Table,and performed Raven Standard Progressive Matrices Test( RSPM),Digit Span( DSP) and Digit Symbol Test( DSY) to assess cognitive functions,at the same time detected P300 and Eysenck Personality Questionnaire( EPQ). In 60 healthy subjects as controls. Results Gender was positive related with RSPM and DSY( r = 0. 452、0. 369,P < 0. 01); age and neuroticism factor were negative related with RSPM,DSP and DSY; level of education,marital status,N2 latency,P2P3 amplitude were positive related with DSP( r = 0. 302 ~ 0. 481,P < 0. 01); economic status and N1 latency were positive related with RSPM,DSP and DSY; family relationships and psychoticism factor were negative related with DSP,DSY; psychological factor,clinical course and subtypes had no related with cognitive functions; intravert-extravert factor and N1N2 amplitude were negative related with RSPM and DSP; lying factor was negative related with RSPM and DSY( r =-0. 570、-0. 195,P< 0. 05 or 0. 01); P2 latency was positive related with DSY( r = 0. 261,P < 0. 05); P3 latency was negative related with DSP( r =-0. 237,P < 0. 05); N2P2 amplitude was negative related with RSPM and DSP( r =-0. 220、-0. 293,P < 0. 05 or 0. 01). Conclusion The influencing factors of cognitive factors in patients with somatoform disorders including age,educational level,marital status,economic status,family relationships,personality traits and P300 potential,but psychological factor,clinical course and subtypes have no effect on cognitive functions.

关 键 词：躯体形式障碍 认知功能 影响因素 

分 类 号：R749[医药卫生—神经病学与精神病学]