Notch信号与细胞凋亡及其在口腔医学的研究进展  

Research progresses of Notch signaling and cell apoptosis in stomatology

作　　者：尹秋蓉 童娟 王胜朝 

机构地区：[1]第四军医大学口腔医院预防科军事口腔医学国家重点实验室,陕西西安710032

出　　处：《牙体牙髓牙周病学杂志》2015年第2期113-117,共5页Chinese Journal of Conservative Dentistry

基　　金：国家自然科学基金资助项目(81170947)

摘　　要：Notch信号通路参与机体多种细胞的凋亡调控,有证据表明在牙齿发育、牙齿损伤与修复、以及口腔肿瘤中均有Notch信号参与并可能与细胞凋亡调控相关。本文就Notch信号对细胞凋亡调控及其在口腔医学领域的研究进展作一综述。Notch signaling pathway regulates apoptosis in multiple cell types. Recent evidences indicate that notch signaling is involved in tooth development,dental pulp injury and repair,oral cancer,and may play important role in regulation of cell apoptosis. Here we review the role of Notch signaling in cell apoptosis with emphasis on research progresses in stomatology.

关 键 词：NOTCH信号 细胞凋亡 口腔医学 

分 类 号：R780.2[医药卫生—口腔医学]