牙周基础治疗对2型糖尿病伴牙周炎与超敏C-反应蛋白的影响  

Effect of Periodontal Therapy on Serum C-reactive Protein in Type 2 Diabetes Patients with Periodontitis

作　　者：王祥芸[1] 张晓渝[1] 胡蓉[1] 杨杨[1] 彭蓓[1] 黄大海[1] 

机构地区：[1]云南省第二人民医院口腔科,云南昆明650021

出　　处：《昆明医科大学学报》2015年第2期128-130,共3页Journal of Kunming Medical University

摘　　要：目的探讨牙周基础治疗对2型糖尿病伴慢性牙周炎患者超敏C-反应蛋白(hs-CRP)、糖化血红蛋白(Hb A1c)的影响.方法将76例2型糖尿病伴慢性牙周炎患者随机分为治疗组(常规降糖治疗+牙周基础治疗)、对照组(仅采用常规降糖治疗),疗程3月,检测治疗前后血清hs-CRP、Hb A1c水平.结果治疗组患者hs-CRP、Hb A1c、探诊深度(PD)、附着丧失(AL)显著下降(P<0.01).结论牙周基础治疗可以减轻2型糖尿病伴牙周炎患者微炎症及牙周炎病变程度,且对有效控制血糖有帮助.Objective To investigate the effect of periodontal therapy on high sensitivity C-reactive protein（hs-CRP） and glycosylated hemoglobin（Hb A1c） in type 2 diabetes patients with periodontitis. Methods Sixty patients with type 2 diabetes and chronic periodontitis were enrolled,they were divided periodontal therapy group and control（without periodontal therapy）. Serum hs-CRP and Hb A1 c,periodontal clinical parameters were tested at baseline and 3 months after initial periodontal therapy. Results Serum hs-CRP, Hb A1 c, probing depth（PD）,attachment loss（AL） decreased significantly 3 months after initial periodontal therapy（P〈0.01,P〈0.01,P〈0.01,P〈0.01）,there were no change in the control group.Conclusion Periodontal therapy may decrease the micro-inflammation and periodontitis in type 2 diabetes with chronic periodontitis,and is helpful in controlling blood sugar.

关 键 词：牙周基础治疗 2型糖尿病 牙周炎 超敏C-反应蛋白 

分 类 号：R781.4[医药卫生—口腔医学]