急性脑梗死在不同时间窗溶栓治疗的效果评价  

Effect Evaluation of Acute Cerebral Infarction in Different Time Window of Thrombolysis Therapy

作　　者：赵立伟[1] 赵艳凤[2] 周丹[1] 宋彧琳[1] 张福鼎[1] 于英霞[1] 

机构地区：[1]辽宁省鞍山市长大医院神经内科,114000 [2]辽宁省鞍山市第四医院肿瘤内科,114000

出　　处：《中国继续医学教育》2015年第5期92-93,共2页China Continuing Medical Education

摘　　要：目的通过对急性脑梗死病例在不同时间窗进行溶栓,探讨其疗效。方法对本院收治的50例急性脑梗死患者进行回顾性分析,根据溶栓时间窗不同将其分为实验组和对照组,每组各25例。实验组发病3 h内进行溶栓;对照组发病3~6 h进行溶栓治疗。对比分析两组治疗效果。结果实验组和对照组的治疗总有效率分别为88%和72%,两组方案的疗效差异具有统计学意义（P〈0.05）。实验组和对照组的不良反应率分别为8%和16%,实验组明显低于对照组。结论患者发病后3 h内进行溶栓治疗可以有效地降低致残率和致死率,能够进一步减缓患者的神经功能障碍,大大提高患者的生存机会,值得在临床上推广应用。Objective To through the cases of acute cerebral infarction in different time window of thrombolysis, discuss the curative effect. Methods 50 cases of patients with acute cerebral infarction were retrospectively analyzed, according to different its thrombolysis time window is divided into the experimental group and control group, each group of 25 cases. Thrombolysis group within 3 h of therapy. Control the onset of 3~6 h thrombolysis therapy. Analysis of two groups of therapeutic effect. Results The experimental group and the control group total effective rate were 88% and 72% respectively, the curative effect of two groups of solution differences statistically significant（P〈0.05）. Experimental group and control group in the adverse reaction rate were 8% and 16% respectively, the experimental group significantly lower than the control group. Conclusion Patients within 3 h after the onset of thrombolysis therapy can effectively reduce the morbidity and mortality, could further slow down the patient＇s nerve dysfunction, greatly improve the patients＇ survival, is worth popularization and application in clinic.

关 键 词：急性脑梗死 不同时间窗 溶栓 疗效 

分 类 号：R743[医药卫生—神经病学与精神病学]