乌鲁木齐地区甲状腺癌与尿碘关系病例对照研究  

The prospective study on thyroid carcinoma correlated with urine iodine level in Urmuqi region

作　　者：钟红[1] 杜江[1] 王晓霞[1] 马斌林[1] 

机构地区：[1]新疆医科大学附属肿瘤医院乳腺甲状腺外科,乌鲁木齐830011

出　　处：《肿瘤研究与临床》2015年第2期95-97,共3页Cancer Research and Clinic

基　　金：新疆维吾尔自治区自然科学基金（2012211）

摘　　要：目的探讨新疆维吾尔自治区乌鲁木齐地区甲状腺癌发病与尿碘含量间的关系,为该地区甲状腺癌患者科学补碘提供依据。方法采用病例对照研究方法,将2012年2月至12月新疆医科大学附属肿瘤医院收治的甲状腺癌100例作为病例组,健康对照组选同所医院门诊体检中心甲状腺功能正常的300名健康者,采集空腹晨尿,采用过硫酸铵消化砷铈催化分光光度法测定所有患者尿碘含量。结果病例组尿碘平均为272.69 μg／L,高于健康对照组的161.40 μg／L,病例组碘营养状况高于对照组（P〈0.05）。碘过量（尿碘浓度〉300 μg ／L）病例组34例（34 %）,健康对照组30例（10 %）,两组间差异有统计学意义（P〈0.05）。结论乌鲁木齐地区甲状腺癌患者碘营养状况高于一般人群,但甲状腺癌发病是否与碘过量有关,有待进一步研究。ObjectiveTo investigate the association of thyroid carcinoma and urine iodine level in Urumqi region, intent to provide the evidence of individual iodine supplement of this region. MethodsIn this case-control study, there were 100 patients with thyroid carcinoma and 300 patients with normal thyroid function as the control group in Xinjiang Tumor Hospital between February 2012 and December 2012 as the case group. All the cases were detected for urine iodine concentration by arsenic-cerium catalytic spectrophotometry. ResultsThe mean level of urinary iodine in the case group （272.69 μg/L） was higher than that in the control group （161.40 μg/L） （P 〈 0.05）. The level of iodine was excessive （urinary iodine 〉 300 μg/L） in 34 % （34/100） patients in the case group and 10 % （30/300） patients in control group （P 〈 0.05）. ConclusionThe average urinary iodine content of the thyroid carcinoma in Urmuqi region are generally higher than that of the healthy control group, which indicates that the iodine nutritional status in patients with thyroid carcinoma are better than that in the general population. The relationship between thyroid carcinoma and excessive iodine intake should be necessary for further study.

关 键 词：甲状腺肿瘤 尿碘 乌鲁木齐 

分 类 号：R736.1[医药卫生—肿瘤]