Salvia miltiorrhiza: Traditional medicinal uses, chemistry, and pharmacology  

作　　者：SU Chun-Yan MING Qian-Liang RAHMAN Khalid HAN Ting QIN Lu-Ping 

机构地区：[1]Department of Pharmacognosy, School of Pharmacy, Second Military Medical University [2]Institute of Medicinal Plant Development, Chinese Academy of Medical Science and Peking Union Medical College [3]Department of Pharmacognosy, School of Pharmacy, Third Military Medical University [4]Faculty of Science, School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University

出　　处：《Chinese Journal of Natural Medicines》2015年第3期163-182,共20页中国天然药物（英文版）

基　　金：supported by the Young Scientist Special Project of the National High Technology Research and Development Program of China(No.2014AA020508);National Nature Science Foundation of China(No.81473301)

摘　　要：Salvia miltiorrhiza Bunge(SM) is a very popular medicinal plant that has been extensively applied for many years to treat various diseases, especially coronary heart diseases and cerebrovascular diseases, either alone or in combination with other Chinese plant-based medicines. Although a large number of studies on SM have been performed, they are scattered across a variety of publications. The present review is an up-to-date summary of the published scientific information about the traditional uses, chemical constituents, pharmacological effects, side effects, and drug interactions with SM, in order to lay the foundation for further investigations and better utilization of SM. SM contains diverse chemical components including diterpenoid quinones, hydrophilic phenolic acids, and essential oils. Many pharmacological studies have been done on SM during the last 30 years, focusing on the cardiovascular and cerebrovascular effects, and the antioxidative, neuroprotective, antifibrotic, anti-inflammatory, and antineoplastic activities. The research results strongly support the notion that SM has beneficial therapeutic properties and has a potential of being an effective adaptogenic remedy.Salvia miltiorrhiza Bunge （SM） is a very popular medicinal plant that has been extensively applied for many years to treat various diseases, especially coronary heart diseases and cerebrovascular diseases, either alone or in combination with other Chinese plant-based medicines. Although a large number of studies on SM have been performed, they are scattered across a variety of publications. The present review is an up-to-date summary of the published scientific information about the traditional uses, chemical constituents, pharmacological effects, side effects, and drug interactions with SM, in order to lay the foundation for further investigations and better utilization of SM. SM contains diverse chemical components including diterpenoid quinones, hydrophilic phenolic acids, and essential oils. Many pharmacological studies have been done on SM during the last 30 years, focusing on the cardiovascular and cerebrovascular effects, and the antioxidative, neuroprotective, antifibrotic, anti-inflammatory, and antineoplastic activities. The research results strongly support the notion that SM has beneficial therapeutic properties and has a potential of being an effective adaptogenic remedy.

关 键 词：DANSHEN Cardiovascular diseases ANTITUMOR Side effect Review 

分 类 号：R284[医药卫生—中药学] R965[医药卫生—中医学]